Bepirovirsen
Cat. No.: DC71481
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Chemical Structure
1403787-62-1
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Field of application
Bepirovirsen is an antisense oligonucleotide targeting all HBV messenger RNAs. Bepirovirsen leads to reductions in HBV-derived RNAs, HBV DNA and viral proteins. Bepirovirsen can be used for the research of chronic HBV infection. Bepirovirsen binding site sequence (GCACTTCGCTTCACCTCTGC).
| Cas No.: |
1403787-62-1 |
| Chemical Name: |
Bepirovirsen |
| Synonyms: |
Bepirovirsen |
| Purity: |
>95% |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Target: |
HBV RNA
|
| In Vivo: |
Bepirovirsen (22-50 mg/kg/week; s.c. twice weekly for week 1 and once weekly for weeks 2-4) reduces hepatic HBV RNA and DNA in HBV-transgenic mice. |
| In Vitro: |
Bepirovirsen (16-250 nM; 16 h) reduces hepatitis B virus (HBV) RNA, DNA, and viral proteins in HepG2.2.15 cells. |
MSDS
| TITLE |
DOWNLOAD |
| MSDS_35716_DC71481_2411969-39-4 |
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COA
| LOT NO. |
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