Chiauranib
Cat. No.: DC72116
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Chemical Structure
1256349-48-0
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Field of application
Chiauranib (CS2164) selectively inhibits multiple kinase targets aurora B kinase (AURKB), colony-stimulating factor 1 receptor (CSF1R), and vascular endothelial growth factor receptor (VEGFR)/platelet-derived growth factor receptor (PDGFR)/c-Kit , thereby inhibiting the rapid proliferation of tumor cells, enhancing the antitumor immunity, and inhibiting tumor angiogenesis, to achieve the anti-tumor efficacy.
Cas No.: |
1256349-48-0 |
Chemical Name: |
Chiauranib |
Synonyms: |
CS 2164;Chiauranib;N-(2-Aminophenyl)-6-[(7-methoxy-4-quinolinyl)oxy]-1-naphthalenecarboxamide;F40IRN5981;CS2164;N-(2-aminophenyl)-6-(7-methoxyquinolin-4-yl)oxynaphthalene-1-carboxamide;chiauranib (pseudo INN);GTPL10475;example 32 [US20100298358A1];E77807;N-(2-aminophenyl)-6-(7-methoxyquinolin-4-yloxy)-1-naphthamide;N-(2-Aminophenyl)-6-((7-methoxyquinolin-4-yl)oxy)-1-naphthamide;EX-A6106;EX-A6106;EX-A6106;EX-A6106;EX-A6106;EX-A6106;CHIAURANIB [WHO-DD];CHIAURANIB [WHO-DD];CHIAURANIB [WHO-DD];CHIAURANIB [WHO-DD];CHIAURANIB [WHO-DD];CHIAURANIB [WHO-DD];CHIAURANIB [WHO-DD];BRKWREZNORONDU-UHFFFAOYSA-N;BRKWREZNORONDU-UHFFFAOYSA-N;BRKWREZNORONDU-UHFFFAOYSA-N;BRKWREZNORONDU-UHFFFAOYSA-N;BRKWREZNORONDU-UHFFFAOYSA-N;BRKWREZNORONDU-UHFFFAOYSA-N;BRKWREZNORONDU-UHFFFAOYSA-N;ibcasertib [INN];ibcasertib [INN];ibcasertib [INN];ibcasertib [INN];ibcasertib [INN];ibcasertib [INN];ibcasertib [INN];AKOS040754703;AKOS040754703;AKOS040754703;AKOS040754703;AKOS040754703;AKOS040754703;AKOS040754703;AS-84740;AS-84740;AS-84740;AS-84740;AS-84740;AS-84740;AS-84740;UNII-F40IRN5981;UNII-F40IRN5981;UNII-F40IRN5981;UNII-F40IRN5981;UNII-F40IRN5981;UNII-F40IRN5981;UNII-F40IRN5981;HY-124526;HY-124526;HY-124526;HY-124526;HY-124526;HY-124526;HY-124526;ibcasertib;ibcasertib;ibcasertib;ibcasertib;ibcasertib;ibcasertib;ibcasertib;N-(2-aminophenyl)-6-[(7-methoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide;N-(2-aminophenyl)-6-[(7-methoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide;N-(2-aminophenyl)-6-[(7-methoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide;N-(2-aminophenyl)-6-[(7-methoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide;N-(2-aminophenyl)-6-[(7-methoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide;N-(2-aminophenyl)-6-[(7-methoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide;SCHEMBL3757428;SCHEMBL3757428;SCHEMBL3757428;SCHEMBL3757428;SCHEMBL3757428;N-(2-aminophenyl)-6-[(7-methoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide;SCHEMBL3757428;1-Naphthalenecarboxamide, N-(2-aminophenyl)-6-[(7-methoxy-4-quinolinyl)oxy]-;1-Naphthalenecarboxamide, N-(2-aminophenyl)-6-[(7-methoxy-4-quinolinyl)oxy]-;1-Naphthalenecarboxamide, N-(2-aminophenyl)-6-[(7-methoxy-4-quinolinyl)oxy]-;SCHEMBL3757428;1-Naphthalenecarboxamide, N-(2-aminophenyl)-6-[(7-methoxy-4-quinolinyl)oxy]-;1-Naphthalenecarboxamide, N-(2-aminophenyl)-6-[(7-methoxy-4-quinolinyl)oxy]-;1-Naphthalenecarboxamide, N-(2-aminophenyl)-6-[(7-methoxy-4-quinolinyl)oxy]-;CHEMBL5095033;CHEMBL5095033;CHEMBL5095033;CHEMBL5095033;1-Naphthalenecarboxamide, N-(2-aminophenyl)-6-[(7-methoxy-4-quinolinyl)oxy]-;CHEMBL5095033;CHEMBL5095033;1256349-48-0;1256349-48-0;1256349-48-0;1256349-48-0;CHEMBL5095033;1256349-48-0;1256349-48-0;CS-2164;CS-2164;CS-2164;CS-2164;1256349-48-0;CS-2164;CS-2164;CS-0086815;CS-0086815;CS-0086815;CS-0086815;CS-2164;CS-0086815;CS-0086815;CS-0086815 |
SMILES: |
O(C1C([H])=C([H])N=C2C([H])=C(C([H])=C([H])C=12)OC([H])([H])[H])C1C([H])=C([H])C2C(C(N([H])C3=C([H])C([H])=C([H])C([H])=C3N([H])[H])=O)=C([H])C([H])=C([H])C=2C=1[H] |
Formula: |
C27H21N3O3 |
M.Wt: |
435.4739 |
Purity: |
98% |
Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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