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DNQX disodium salt

  Cat. No.:  DC10673   Featured
Chemical Structure
1312992-24-7
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More than 5000 active chemicals with high quality for research!
Field of application
DNQX is a elective non-NMDA antagonist
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1312992-24-7
Chemical Name: DNQX disodium salt
SMILES: O=C1[N-]C2=C(C=C([N+]([O-])=O)C([N+]([O-])=O)=C2)[N-]C1=O.[Na+].[Na+]
Formula: C8H2N4Na2O6
M.Wt: 296.100
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: DNQX (FG 9041) disodium salt, a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively)[1].
In Vivo: DNQX (FG 9041), a specific AMPA receptor antagonist, given as either a 5 mg/kg or 10 mg/kg intraperitoneal dose or into the lateral cerebral ventricle (5 μl of 0.5 mg/ml) significantly diminishes phencyclidine (PCP) (40 mg/kg) and ketamine (80, 100, 120 mg/kg) hsp70 induction in the posterior cingulate and retrosplenial cortex[3].
In Vitro: DNQX (FG 9041) disodium salt selectively depolarizes thalamic reticular nucleus (TRN) neurons[2].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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