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Home > Inhibitors & Agonists > Membrane Transporter/Ion Channel > iGluR

DNQX

  Cat. No.:  DC10672   Featured
Chemical Structure
2379-57-9
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More than 5000 active chemicals with high quality for research!
Field of application
DNQX is a elective non-NMDA antagonist
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2379-57-9
Chemical Name: 6,7-Dinitro-1,4-dihydroquinoxaline-2,3-dione
Synonyms: 2,3-Quinoxalinedione,1,4-dihydro-6,7-dinitro-;Dnqx;1,4-Dihydro-6,7-Dinitro-2,3-Quinoxalinedione;6,7-Dinitro-2,3-dihydroxyquinoxaline;6,7-DINITROQUINOXALINE-2,3-DIONE;6,7-dinitro-1,4-dihydroquinoxaline-2,3-dione;6,7-Dinitroquinoxaline-2,3(1H,4H)-dione;6,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione;6,7-Dinitroquinoxaline-2,3-(1H,4H)-dione;FG 9041;6,7-Dinitroquinoxaline-2,3-dione (DNQX);2,3-Quinoxalinedione, 1,4-dihydro-6,7-dinitro-;62T278S1MX;1ftl;Oprea1_127694;Lopac0_000345;MLS000705107;BPBio1_001176;C8H4N4O6
SMILES: O=C1C(N([H])C2=C([H])C(=C(C([H])=C2N1[H])[N+](=O)[O-])[N+](=O)[O-])=O
Formula: C8H4N4O6
M.Wt: 252.1406
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: DNQX is a AMPA receptor antagonists.target: AMPA receptorIn vitro: DNQX, added 2 h after cell plating, induces a dose-dependent neurotoxicity.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC8824 Traxoprodil Traxoprodil is an NMDA ε 2 (NR2B) antagonist that has been studied as an alternative to serotonin selective reuptake inhibitors.
DC7863 Talampanel (GYKI 53773) Talampanel is a novel anticonvulsant that acts as an allosteric inhibitor of the AMPA receptor.
DC8175 Rapastinel(GLYX-13) Rapastinel(GLYX-13) is a NMDA receptor partial agonist that acts at the glycine site.
DC8307 QNZ46 QNZ is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist (IC50 values are 3, 6, 229, and >300, >300 μM for NR2D, NR2C, NR2A, NR2B, and GluR1, respectively).
DC7226 Perampanel(E2007） Perampanel(E2007; ER 155055-90) is a selective noncompetitive AMPA-type glutamate receptor antagonist which has demonstrated anticonvulsant activity in experimental seizure models and antiepileptic activity in clinical trials.
DC7989 PEPA PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.
DC11382 NYX-2925 NYX-2925 is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Learning and Memory.
DC7576 NVP-AAM077 NVP-AAM077 is a potent antagonist for NMDA receptors.
DC11406 NBQX NBQX is a potent aminomethylphosphonic acid receptor (AMPAR) antagonist with an IC50 of 0.7 ± 0.1 μM.
DC7194 MDL 29951 MDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo.
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