Enavogliflozin|CAS 1415472-28-4|DC Chemicals

Cas No.:	1415472-28-4
Chemical Name:	Enavogliflozin
Synonyms:	Enavogliflozin;Z5MR2Y1IJJ;(2S,3R,4R,5S,6R)-2-[7-chloro-6-[(4-cyclopropylphenyl)methyl]-2,3-dihydro-1-benzofuran-4-yl]-6-(hydroxymethyl)oxane-3,4,5-triol;Enavogliflozin [INN];GCC5694A;GTPL11905;BDBM159529;DWP16001;compound 14g [PMID: 34813882];US9034921, E172;(1S)-1,5-Anhydro-1-C-(7-chloro-6-((4-cyclopropylphenyl)methyl)-2,3-dihydro-4-benzofuranyl)-D-glucitol;D-Glucitol, 1,5-anhydro-1-C-(
SMILES:	ClC1C(C([H])([H])C2C([H])=C([H])C(=C([H])C=2[H])C2([H])C([H])([H])C2([H])[H])=C([H])C(=C2C=1OC([H])([H])C2([H])[H])[C@@]1([H])[C@@]([H])([C@]([H])([C@@]([H])([C@@]([H])(C([H])([H])O[H])O1)O[H])O[H])O[H]
Formula:	C₂₄H₂₇ClO₆
M.Wt:	446.9206
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC46870	Enavogliflozin	Enavogliflozin (DWP-16001), an antidiabetic agent, is an orally active, best-in-class and selective sodium-glucose cotransporter-2 (SGLT-2) inhibitor.
DC3108	PF-04971729 (Ertugliflozin)	PF-04971729 is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2, is currently in phase 2 trials for the treatment of diabetes mellitus.
DC7921	Sotagliflozin (LX-4211)	LX-4211 is a potent dual SGLT2/1 inhibitor; Antidiabetic agents.
DC6904	DAPAGLIFLOZIN	Dapagliflozin, also known as BMS-512148, is a drug used to treat type 2 diabetes approved in 2012 by FDA. Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2) which are responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter mechanism causes blood glucose to be eliminated through the urine. In clinical trials, dapagliflozin lowered HbA1c by 0.6 versus placebo percentage points when added to metformin.
DC3111	Canagliflozin	Canagliflozin is a highly potent and selective SGLT2 inhibitor for CHO-hSGLT2, CHO-rSGLT2 and CHO-mSGLT2 with IC50 of 4.4 nM, 3.7 nM and 2 nM, respectively.
DC8186	Bexagliflozin3	Bexagliflozin is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 μM /2 nM in SGLT1 /SGLT2 respectively.