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Home > Inhibitors & Agonists > GPCR > Calcium-sensing Receptor (CaSR)

Evocalcet

  Cat. No.:  DC72765   Featured
Chemical Structure
870964-67-3
For research use only. We do not sell to patients.
Package Sale price Available Quantity Operating
100 mg$250.00in stock
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250 mg$500.00in stock
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1 g$1000.00in stock
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More than 5000 active chemicals with high quality for research!
Field of application
Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic [Ca2+] concentrations with an EC50 value of 92.7 nM in hCaR-HEK293 cells.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 870964-67-3
Chemical Name: Evocalcet
Synonyms: Evocalcet;E58MLH082P;2-(4-((S)-3-(((R)-1-(naphthalen-1-yl)ethyl)amino)pyrrolidin-1-yl)phenyl)acetic acid;2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]acetic acid;Evocalcet [INN];2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid;H43;Orkedia (TN);Evocalcet (JAN/INN);GTPL9042;KHK7580;DB12388;SB18696;Benzeneacetic acid, 4-((3S)-3-(((1R)-1-(1-naphthalenyl)ethyl)ami
SMILES: OC(CC1C=CC(=CC=1)N1CC[C@@H](C1)N[C@H](C)C1=CC=CC2C=CC=CC1=2)=O
Formula: C24H26N2O2
M.Wt: 374.475446224213
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_37288_DC72765_870964-67-3
COA
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Cat. No. Product name Field of application
DC72765 Evocalcet Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic [Ca2+] concentrations with an EC50 value of 92.7 nM in hCaR-HEK293 cells.
DC8801 Cinacalcet (AMG-073) Cinacalcet(AMG-073) is an orally active, second-generation calcimimetic compound; AMG 073 represents a new class of compounds for the treatment of hyperparathyroidism.
DC5083 Cinacalcet (AMG-073) HCl AMG-073 HCl (Cinacalcet HCl) represents a new class of compounds for the treatment of hyperparathyroidism.
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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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