GLX7013114|CAS |DC Chemicals

Cas No.:
Chemical Name:	GLX7013114
Synonyms:	GLX-7013114
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC70434	GLX7013114	GLX7013114 (GLX-7013114) is a novel selective NADPH oxidase 4 (Nox4) inhibitor with IC50 of 0.3 uM in in CJ Nox4 HEK 293 cell asays.GLX7013114 displays no activity against Nox 1/2/3/5, as well as Glucose oxidase and Xanthine oxidase; does not display any redox activity.GLX7013114 inhibits TGFβ-induced upregulation of mesenchymal genes.GLX7013114 protected islet cells against both cytokines and high glucose + palmitate.
DC10841	VAS 2870	VAS2870 is a selective inhibitor of the NADPH oxidases.
DC11009	GLX351322	GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μ M.
DC8118	GKT137831(Setanaxib)	GKT137831 is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 140±40 nM and 110±30 nM; a potent inhibitor of fibrosis and hepatocyte apoptosis.