IDO1-IN-12

  Cat. No.:  DC48218  
Chemical Structure
2379570-48-4
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More than 5000 active chemicals with high quality for research!
Field of application
IDO1-IN-12 is a potent and orally available IDO1 inhibitor.
Cas No.: 2379570-48-4
Chemical Name: IDO1-IN-12
Formula: C21H19F3N2O2
M.Wt: 388.38
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_32109_DC48218_2379570-48-4
COA
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Cat. No. Product name Field of application
DC72667 CAY10581 CAY10581, a pyranonaphthoquinone derivative, is a highly specific and reversible uncompetitive IDO Inhibitor with an IC50 of 55 nM.
DC72373 ZC0109 ZC0109 is a dual inhibitor of IDO1 and thioredoxin reductase 1 (TrxR1) with IC50s of 50 nM and 3.0 μM, respectively. ZC0109 induces ROS accumulation and cell cycle arrest at G1/S phase, thus leads to cancer cells Apoptosis.
DC72372 DP00477 DP00477 is a potent IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor with an IC50 value of 7.0 µM. DP00477 has the potential for the research of cancer.
DC71383 ZC0101 ZC0101 is a potent, orally active IDO1 and TrxR dual inhibitor with IC50 values of 0.084 μM and 7.98 μM, respectively. ZC0101 effectively induces apoptosis and ROS accumulation in cancer cells.
DC49741 IDO1-IN-15 IDO1-IN-15 is a potent IDO1 inhibitor (IC50=127 nM). IDO1-IN-15 has comparable potency against IDO1 enzyme in vitro with Epacadostat.
DC49740 IDO1-IN-14 IDO1-IN-14 (compound 4a) is a potent IDO1 inhibitor with an IC50 of 396.9 nM. IDO1-IN-14 has cellular IDO1 inhibition (HeLa EC50=3393 nM).
DC49739 IDO1-IN-13 IDO1-IN-13 (compound 27a) is a potent IDO1 inhibitor with an IC50 of 61.6 nM. IDO1-IN-13 has cellular IDO1 inhibition (HeLa EC50= 30 nM). IDO1-IN-13 decreases 51% of the kyn/trp ratio in SK-OV-3 xenograft tumor tissues.
DC48664 IDO1/2-IN-1 IDO1/2-IN-1 (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 exhibits antitumor activies. Orally active.
DC48218 IDO1-IN-12 IDO1-IN-12 is a potent and orally available IDO1 inhibitor.
DC48217 IDO1-IN-11 IDO1-IN-11 is an IDO1 inhibitor with an IC50 value of 0.6 nM.
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