Cas No.: | 1233533-04-4 |
Chemical Name: | 3,4-Dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one |
Synonyms: | kb-NB142-70;3,4-Dihydro-9-hydroxy-[1]benzothieno-[2,3-f]-1,4-thiazepin-5(2H)-one;3,4-Dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one;kb NB 142-70;AG-L-65866;CHEBI:1169969;CHEMBL1672571;CS-1091;CTK8G0429;QCR-15;SureCN9920595;9-hydroxy-3,4-dihydro-2H-[1]benzothiolo[2,3-f][1,4]thiazepin-5-one;DHUAGGSHTKPOHU-UHFFFAOYSA-N;GTPL9369;AOB1401;SYN5189;HMS3740G15;BCP06729;BDBM50336960;3758AH;AB0094895;kb- |
SMILES: | S1C([H])([H])C([H])([H])N([H])C(C2=C1C1C([H])=C(C([H])=C([H])C=1S2)O[H])=O |
Formula: | C11H9NO2S2 |
M.Wt: | 251.3247 |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | kb NB 142-70 is a selective protein kinase D (PKD) inhibitor. Demonstrates a 7-fold increase in inhibition potency as an analog of CID 755673. Reported to demonstrate prominent cytotoxic and anti-proliferative effects in vitro. Additionally noted to inhibit cell migration and invasion in a prostate cancer cell line. kb NB 142-70 is an inhibitor of PKC μ, PKC ν and PKD2. For the detailed information of kb NB 142-70, the solubility of kb NB 142-70 in water, the solubility of kb NB 142-70 in DMSO, the solubility of kb NB 142-70 in PBS buffer, the animal experiment (test) of kb NB 142-70, the cell expriment (test) of kb NB 142-70, the in vivo, in vitro and clinical trial test of kb NB 142-70, the EC50, IC50,and affinity,of kb NB 142-70, For the detailed information of kb NB 142-70, the solubility of kb NB 142-70 in water, the solubility of kb NB 142-70 in DMSO, the solubility of kb NB 142-70 in PBS buffer, the animal experiment (test) of kb NB 142-70, the cell expriment (test) of kb NB 142-70, the in vivo, in vitro and clinical trial test of kb NB 142-70, the EC50, IC50,and affinity,of kb NB 142-70, Please contact DC Chemicals. |