LEO 134310

  Cat. No.:  DC70563   Featured
Chemical Structure
2089130-74-3
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Field of application
LEO 134310 (LP 0155) is a non-steroidal, potent and selective glucocorticoid receptor (GR) agonist (EC50=2 nM, hPBMC)
Cas No.: 2089130-74-3
Chemical Name: Benzoic acid, 4-​[(1R,​2S)​-​1-​(4-​cyclopropylphenyl)​-​2-​[[[(2R)​-​tetrahydro-​2-​furanyl]​carbonyl]​amino]​propoxy]​-​, (3S)​-​1-​[[(3R)​-​tetrahydro-​5-​oxo-​3-​furanyl]​carbonyl]​-​3-​piperidinyl ester
SMILES: C1CC1C1C=CC(C([C@H](C)NC(=O)[C@H]2CCCO2)OC2C=CC(C(O[C@@H]3CN(C(=O)[C@H]4COC(C4)=O)CCC3)=O)=CC=2)=CC=1
Formula: C34H40N2O8
M.Wt: 604.69
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC70563 LEO 134310 LEO 134310 (LP 0155) is a non-steroidal, potent and selective glucocorticoid receptor (GR) agonist (EC50=2 nM, hPBMC)
DC11203 ORIC-101 ORIC-101 (ORIC101) is a highly potent, selective steroidal glucocorticoid receptor (GR) antagonist (IC50=5.6 nM) with reduced androgen receptor (AR) agonistic activity.
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