NX-1607
Cat. No.: DC74301
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Chemical Structure
2573775-59-2
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Field of application
NX-1607 (Compound 23) is an inhibitor of Cbl-b, an E3 enzyme in the ubiquitin-proteasome pathway, with an IC50 value of less than 1 nM. NX-1607 can be used in cancer research.
Cas No.: |
2573775-59-2 |
Chemical Name: |
Cbl-b-IN-3 |
Synonyms: |
1H-Isoindol-1-one, 2,3-dihydro-2-[3-[cis-3-methyl-1-(4-methyl-4H-1,2,4-triazol-3-yl)cyclobutyl]phenyl]-6-[[(3S)-3-methyl-1-piperidinyl]methyl]-4-(trifluoromethyl)-;Cbl-b-IN-3 |
SMILES: |
C1(=O)C2=C(C(C(F)(F)F)=CC(CN3CCC[C@H](C)C3)=C2)CN1C1=CC=CC([C@@]2(C3N(C)C=NN=3)C[C@H](C)C2)=C1 |
Formula: |
C30H34F3N5O |
M.Wt: |
537.619077205658 |
Purity: |
>98% |
Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
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