PRMT5-IN-11

  Cat. No.:  DC47612  
Chemical Structure
2567564-33-2
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More than 5000 active chemicals with high quality for research!
Field of application
PRMT5-IN-11 is a promising structure-dependent inhibition of the protein methyltransferase PRMT5:MEP50 complex in the (sub)micromolar range.
Cas No.: 2567564-33-2
Chemical Name: PRMT5-IN-11
Formula: C13H17N5O4
M.Wt: 307.31
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
TITLE DOWNLOAD
MSDS_31462_DC47612_2567564-33-2
COA
LOT NO. DOWNLOAD
Cat. No. Product name Field of application
DC47618 PRMT5-IN-10 PRMT5-IN-10 has promising structure-dependent inhibition of the protein methyltransferase PRMT5:MEP50 complex.
DC47617 EED ligand 1 EED ligand 1 is a diverse, potent, and efficacious inhibitor that target the EED subunit of the polycomb repressive complex 2 (PRC2) methyltransferase.
DC47615 PRMT5-IN-9 PRMT5-IN-9 is a novel PRMT5 inhibitor for treating cancer, with an IC50 of 0.01 μM.
DC47613 PRMT5-IN-12 PRMT5-IN-12 shows remarkable inhibitory activity on PRMT5.
DC47612 PRMT5-IN-11 PRMT5-IN-11 is a promising structure-dependent inhibition of the protein methyltransferase PRMT5:MEP50 complex in the (sub)micromolar range.
DC47611 PRMT5-IN-14 PRMT5-IN-14 is a PRMT5 inhibitor to treat cancer, sickle cell, and hereditary persistence of foetal hemoglobin (HPFH) mutations.
DC47610 PRMT5-IN-3 PRMT5-IN-3 is a PRMT5 inhibitor that exhibits synthetic lethality to tumor cells but produce few side effects combined with DNA damaging agents.
DC47609 PRMT1-IN-1 PRMT1-IN-1 is a PRMT1 inhibitor.
DC47608 EZH2-IN-2 EZH2-IN-2 is a EZH2 inhibitor extracted from patent WO2018133795A1, Compound Example 69, with an IC50 of 64 nM. EZH2-IN-2 can be used for the research of cancer or precancerous condition related to EZH2 activity.
DC47264 MS67 MS67 is a potent and selective WD40 repeat domain protein 5 (WDR5) degrader with a Kd of 63 nM. MS67 is inactive against other protein methyltransferases, kinases, GPCRs, ion channels, and transporters. MS67 shows potent acticancer effects.
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