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More than 5000 active chemicals with high quality for research!
Field of application
pyCTZ (Pyridyl CTZ) TFA, a pyridyl-modified derivative of Coelenterazine (CTZ), serves as an ATP-independent substrate for LumiLuc luciferase. This compound produces intense blue bioluminescence upon interaction with luciferases and is particularly effective in aequorin-based calcium sensing applications.
Ac-LETD-AFC is a caspase-8 fluorogenic substrate. Ac-LETD-AFC can measure caspase-8 fluorogenic activity and can be used for the research of cancer cell apoptosis and oxidative stress metabolism.
D-Val-Gly-Arg-p-nitroaniline (D-VGR-pNA) is a synthetic chromogenic peptide substrate specifically designed for assessing the enzymatic activity of tissue plasminogen activator (tPA), including its isoforms tPA I and tPA II. Upon cleavage by tPA, the release of p-nitroaniline (pNA) generates a measurable colorimetric signal, enabling precise quantification of amidolytic activity. This substrate is widely utilized in biochemical assays to study tPA’s role in fibrinolysis and to evaluate its enzymatic kinetics in both research and diagnostic applications.
Cephalofurimazine (CFz) is a NanoLuc substrate optimized for enhanced brain performance. When paired with Antares luciferase, it generates over 20 times more signal from the brain compared to the traditional combination of D-luciferin and firefly luciferase.
Coelenterazine h, a modified form of Coelenterazine, exhibits heightened sensitivity to Ca2+ compared to the native compound, making it an effective tool for detecting subtle fluctuations in Ca2+ concentrations.
Fluorofurimazine is an advanced furimazine derivative with enhanced aqueous solubility, allowing for greater signal output compared to furimazine in bioluminescence imaging. This compound supports higher substrate concentrations and delivers improved sensitivity for in vivo optical imaging applications.
ViviRen is a synthetic analog of coelenterazine specifically designed for bioluminescence imaging (BLI), offering enhanced performance in visualizing biological processes.
For-Met-Leu-pNA is an N-formylated peptide substrate specifically designed for use in deformylase activity assays, providing a reliable tool for studying enzyme function.