RET-IN-14

  Cat. No.:  DC50275   Featured
Chemical Structure
2755843-62-8
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More than 5000 active chemicals with high quality for research!
Field of application
RET-IN-14 (compound 49) is a potent RET inhibitor with IC50s of <0.51 nM, 9.3 nM, 1.3 nM, 9.2 nM, 15 nM for RET (WT), RET (G810R), RET (V804M), BTK and BTK (C481S), respectively. RET-IN-14 has the potential for tumors research
Cas No.: 2755843-62-8
Chemical Name: RET-IN-14
Synonyms: RET-IN-14
SMILES: NC1=C(C2C=CC(=CC=2)NC(=O)OC)C2=NCC3=CC(=CN=C3O[C@H](CNC(C3C=NN1C=3N2)=O)C)F |t:15,&1:24|
Formula: C24H23FN8O4
M.Wt: 506.489027261734
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC50275 RET-IN-14 RET-IN-14 (compound 49) is a potent RET inhibitor with IC50s of <0.51 nM, 9.3 nM, 1.3 nM, 9.2 nM, 15 nM for RET (WT), RET (G810R), RET (V804M), BTK and BTK (C481S), respectively. RET-IN-14 has the potential for tumors research
DC10936 GSK3179106 GSK3179106 (GSK-3179106, GSK 3179106) is a potent, selective, first-in-class and gut-restricted with IC50 of 0.4 and 11 nM in the biochemical assay and cellular assay respectively.
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