RJR-2403 hemioxalate

  Cat. No.:  DC70738  
Chemical Structure
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More than 5000 active chemicals with high quality for research!
Field of application
RJR-2403 (Rivanicline, Metanicotine) is a potent, selective neuronal nicotinic ACh (nAChR) agonist with high affinity to rat brain cortex (Ki=26 nM), does not significantly activate muscle type nAChRs or muscarinic receptors; RJR-2403 is comparable to nicotine in activating rat thalamic synaptosomes with EC50 of 732 nM; significantly improves passive avoidance retention after scopolamine-induced amnesia and enhanced both working and reference memory in rats, also demonstrates greatly reduced cardiovascular effects; exerts its antinociceptive effect via nicotinic rather than either opioid or muscarinic mechanisms.
Cas No.:
Chemical Name: RJR-2403 hemioxalate
Synonyms: Rivanicline hemioxalate;Metanicotine hemioxalate;RJR 2403 hemioxalate;RJR2403 hemioxalate
Formula: C11H15N2O2
M.Wt: 207.23
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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