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Sanofi-14h

  Cat. No.:  DC73795  
Chemical Structure
1426214-64-3
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More than 5000 active chemicals with high quality for research!
Field of application
Sanofi-14h is a selective inhibitor of the AGC family kinase SGK3, blocks DMXAA-stimulated IRF3-promoter activity with IC50 of 1.73 uM, inhibits IFNβ production under STING stimulation.
Cas No.: 1426214-64-3
Chemical Name: Sanofi-14h
Formula: C17H12Cl2N6O2S
M.Wt: 435.28
MSDS
Cat. No. Product name Field of application
DC48893 SGK1-IN-4 SGK1-IN-4 (compound 17a) is a highly selective, orally active SGK1 inhibitor. SGK1-IN-4 can be used for osteoarthritis research.
DC73795 Sanofi-14h Sanofi-14h is a selective inhibitor of the AGC family kinase SGK3, blocks DMXAA-stimulated IRF3-promoter activity with IC50 of 1.73 uM, inhibits IFNβ production under STING stimulation.
DC49756 SGK1-IN-3 SGK1-IN-3 (compound 3a) is a potent and orally active inhibitor of SGK1. The serine/threonine kinase SGK1 is an activator of the β-catenin pathway and a powerful stimulator of cartilage degradation that is found to be upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 has the potential for the research of osteoarthritis.
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