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SKLB0565

  Cat. No.:  DC71499  
Chemical Structure
2414607-10-4
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More than 5000 active chemicals with high quality for research!
Field of application
SKLB0565 is a potent tubulin inhibitor. SKLB0565 shows significant anti-proliferative activity against CRC (colorectal carcinoma) cell lines, with IC50 values ranging from 0.012 μM to 0.081 μM. SKLB0565 causes G2/M phase arrest and mitochondria-mediated intrinsic apoptosis. SKLB0565 inhibits cell migration and disrupted the tube formation of HUVECs.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2414607-10-4
Chemical Name: SKLB0565
SMILES: O=C1C(CNC2=C3N=CN(C4CCCC4)C3=NC(Cl)=N2)=C(CC)C=C(CC)N1
Formula: C20H25ClN6O
M.Wt: 400.91
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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