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SR18662

Cat. No.: DC39108 Featured

Chemical Structure

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Field of application

SR18662 is an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM. SR18662 reduces the viability of multiple colorectal cancer cell lines. SR18662 induces apoptosis.

Chemicals Properties Biological activity COA & MSDS Related products Datasheet

Cas No.:
Chemical Name:	SR18662
Synonyms:	SR18662;SR-18662;SR 18662
SMILES:	ClC1=CC(/C=C/C(NCC(N2CCN(CC2)S(C)(=O)=O)=O)=O)=CC=C1Cl
Formula:	C₁₆H₁₉Cl₂N₃O₄S
M.Wt:	420.31
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	[1]. Julie Kim,et al.The Novel Small-Molecule SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitroand In Vivo.Mol Cancer Ther.2019 Nov;18(11):1973-1984.

MSDS

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MSDS_20496_DC39108

COA

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Cat. No.	Product name	Field of application
DC48418	SR15006	SR15006 is a inhibitor of Krüppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells).
DC39108	SR18662	SR18662 is an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM. SR18662 reduces the viability of multiple colorectal cancer cell lines. SR18662 induces apoptosis.

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