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Sulfo-SPDB-DGN462

  Cat. No.:  DC46214  
Chemical Structure
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More than 5000 active chemicals with high quality for research!
Field of application
Sulfo-SPDB-DGN462 is a drug-linker conjugate for ADC. Sulfo-SPDB-DGN462 consists a toxin DGN462 conjugated to the cleavable Sulfo-SPDB linker. DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.:
Chemical Name: Sulfo-SPDB-DGN462
SMILES: O=C1N2[C@](CC3=C2C=CC=C3)([H])CNC4=CC(OCC5=CC(N(C(C(C)(C)SSCCC(S(=O)(O)=O)C(ON6C(CCC6=O)=O)=O)=O)CCOCCOCCOC)=CC(COC7=C(OC)C=C8C(N9[C@](CC%10=C9C=CC=C%10)([H])C=NC8=C7)=O)=C5)=C(OC)C=C14
Formula: C61H66N6O17S3
M.Wt: 1251.40
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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