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WT IDH1 Inhibitor 2

Cat. No.: DC45831

Chemical Structure

1816272-19-1

For research use only. We do not sell to patients.

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Field of application

WT IDH1 Inhibitor 2 is a wild-type isocitrate dehydrogenase 1 (WT IDH1) inhibitor with an IC50 value of 120 nM. WT IDH1 Inhibitor 2 as a mutant R132H IDH1 inhibitor, is an isomer of GSK321 with some wild-type cross reactivity.

Chemicals Properties Biological activity COA & MSDS Related products Datasheet

Cas No.:	1816272-19-1
Chemical Name:	WT IDH1 Inhibitor 2
SMILES:	O=C(C1=NN(CC2=CC=C(F)C=C2)C3=C1CN(C(C4=CC=CN4)=O)C[C@H]3C)NC5=CC=CC([C@H](O)C)=C5
Formula:	C₂₈H₂₈FN₅O₃
M.Wt:	501.55
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC46300	IDH-C227	IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts.
DC45831	WT IDH1 Inhibitor 2	WT IDH1 Inhibitor 2 is a wild-type isocitrate dehydrogenase 1 (WT IDH1) inhibitor with an IC50 value of 120 nM. WT IDH1 Inhibitor 2 as a mutant R132H IDH1 inhibitor, is an isomer of GSK321 with some wild-type cross reactivity.
DC28343	Mutant IDH1-IN-4	Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.