Edaravone (MCI-186)

Efavirenz is a nonnucleoside HIV-1 reverse transcriptase (RT) inhibitor which selectively inhibits the glucuronidation of 3'-Azido-3'-deoxythymidine β-D-glucuronide, Sodium Salt. Studies suggest that Efavirenz binds to a distinct site of reverse transcrip

Eldecalcitol (ED-71; 2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitamin D3) is an analog of 1,25-dihydroxyvitamin D3 that improves bone mineral density. Eldecalcitol (ED-71; 2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitamin D3) is more efficaci

Elocalcitol

Eltrombopag (SB-497115-GR)

Enalapril maleate (Vasotec)

Epalrestat is an orally active aldose reductase inhibitor that acts on diabetic neuropathy.

Eplerenone, also known as Inspra and CGP-30083, is a selective aldosterone receptor antagonist used to treat hypertension and congestive heart failure. Eplerenone provides marked protection against vascular injury in the kidney and heart.

Eprosartan is a nonpeptide angiotensin II receptor antagonist with IC50 of 9.2 and 3.9 nM in rat and human adrenal cortical membranes, respectively.

Erdosteine

Eribulin is an anticancer drug marketed by Eisai Co. under the trade name Halaven. Eribulin is also known as E7389 and ER-086526, and also carries the US NCI designation NSC-707389. It is used to treat certain patients with breast cancer and liposarcoma.

Eribulin Mesylate (E7389 Mesylate), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and microtubules.

Esomeprazole

Esomeprazole(magnesium)

Estradiol

Ethamsylate is a haemostatic drug, also inhibits biosynthesis and action of those prostaglandins.

Ethionamide

Etodolac is a Cox-2 inhibitor with anti-inflammatory and analgesic activity. Etodolac is shown to inhibit growth and PCNA expression and induce cell cycle arrest in human hepatocellular carcinoma cell lines, in addition to suppressing the occurrence of ab

Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.

Falecalcitriol

Famciclovir (Famvir)

Famotidine is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.

FEBUXOSTAT is an inhibitor xanthine oxidase and xanthine dehydrogenase

Felbamate (Felbatol) is an anticonvulsant drug used in the treatment of epilepsy.

Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker.

Fenbendazole (Panacur)

Fenofibrate is PPARα agonist with EC50 of 18 μM and 30 μM for mouse and human PPARα, respectively.

Fenofibric acid is a lipid regulating agent available as delayed release capsules for oral administration.

Fenoprofen calcium

Fenticonazole nitrate

Fleroxacin (Quinodis)

Flubendazole is a potent broad spectrum anthelmintic.

Fluconazole

Flucytosine (5-Fluorocytosine, 5-FC, Ancobon) is an antifungal drug with IC50 of 0.12 μg/mL in C.albicans.

Flumequine

Fluocinolone acetonide (Flucort-N)

Fluocinonide(Vanos)

Fluoxetine HCl is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

Flupenthixol dihydrochloride is a typical antipsychotic of the thioxanthene class that acts as an antagonist at dopamine D2 receptors (Ki = 0.38 nM) and an inverse agonist at serotonin 5-HT2A receptors (Ki = 7 nM).1 It has also been identified as an inhib

Flurbiprofen (Ansaid)

Fluticasone propionate (Flonase, Veramyst)

Fluvastatin, Sodium Salt is a synthetic inhibitor of HMGCR (HMG-CoA reductase) (IC50 = 40-100 nM for human liver microsomes) that acts as an anti-hypercholesterolemic compound and as an antioxidant. Fluvastatin also inhibits induction of the LDL receptor

Fluvoxamine maleate is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.

Acesulfame potassium is an artificial sweetener. Acesulfame potassium (long-term) affects cognitive functions, potentially via altering neuro-metabolic functions in mice.

For the detailed information of Betamethasone valerate (Betnovate), the solubility of Betamethasone valerate (Betnovate) in water, the solubility of Betamethasone valerate (Betnovate) in DMSO, the solubility of Betamethasone valerate (Betnovate) in PBS buffer, the animal experiment（test） (test) of Betamethasone valerate (Betnovate), the cell expriment (test) of Betamethasone valerate (Betnovate), the in vivo, in vitro and clinical trial test of Betamethasone valerate (Betnovate), the EC50, IC50,and Affinity of Betamethasone valerate (Betnovate),, please contact DC Chemicals..

For the detailed information of Dimesna, the solubility of Dimesna in water, the solubility of Dimesna in DMSO, the solubility of Dimesna in PBS buffer, the animal experiment（test） (test) of Dimesna, the cell expriment (test) of Dimesna, the in vivo, in vitro and clinical trial test of Dimesna, the EC50, IC50,and Affinity of Dimesna,, please contact DC Chemicals..

For the detailed information of Reboxetine mesylate, the solubility of Reboxetine mesylate in water, the solubility of Reboxetine mesylate in DMSO, the solubility of Reboxetine mesylate in PBS buffer, the animal experiment（test） (test) of Reboxetine mesylate, the cell expriment (test) of Reboxetine mesylate, the in vivo, in vitro and clinical trial test of Reboxetine mesylate, the EC50, IC50,and Affinity of Reboxetine mesylate,, please contact DC Chemicals..

For the detailed information of Sulfamethazine, the solubility of Sulfamethazine in water, the solubility of Sulfamethazine in DMSO, the solubility of Sulfamethazine in PBS buffer, the animal experiment（test） (test) of Sulfamethazine, the cell expriment (test) of Sulfamethazine, the in vivo, in vitro and clinical trial test of Sulfamethazine, the EC50, IC50,and Affinity of Sulfamethazine,, please contact DC Chemicals..

Formestane(CGP-32349; 4-OHA) is a selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer.

Fosaprepitant (MK-0517, L-758,298) is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist.

Fudosteine

Furosemide (Lasix) is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema.

Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic pain.

Gabexate Mesylate is a Factor X inhibitor.

Gadodiamide is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. Target: OthersGadodiamide(Omniscan) is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. Gadodiamide is a contrast medium for cranial and spinal magnetic resonance imaging (MRI) and for general MRI of the body after intravenous administration. The product provides contrast enhancement and facilitates visualisation of abnormal structures or lesions in various parts of the body including the central nervous system (CNS). A recent review takes the question of toxicity caused by loss of gadolinium from the complex. "The challenge for nephrologists includes (a) evidence of transmetallation, such as gadolinium deposits in bone, increased urinary zinc excretion, iron-transferrin dissociation or 'spurious hypocalcemia' in exposed people"。

Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase(AChE) inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors.

Ganciclovir

Gemfibrozil (Lopid)

Genipin

Geniposide

Geniposidic acid

Gentamycin sulfate (Gentacycol)

Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as hypoxic/ischemic brain injury, inflammatory bowel disease and spinal and bulbar muscul

Gimeracil(Gimestat) is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which degrades pyrimidine including 5-fluorouracil in the blood; inhibits homologous recombination.

Glimepiride(Amaryl) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg.

Glipizide is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.

Glucosamine (hydrochloride) is a natural product.

Gossypol

Granisetron Hcl(BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

Grape Seed Extract

Guaifenesin(Guaiphenesin)

Haloperidol (Haldol)

Hesperidin

Darunavir(TMC114) is an HIV protease inhibitor,showed potent activity against COVID-19(SARS-COV-2) .

Hydralazine HCl

Hydrochlorothiazide

Hydrocortisone (Cortisol)

Hydroxyflutamide (Hydroxyniphtholide)

Hydroxyurea (Cytodrox)

Hyoscyamine Sulfate

Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor which has been marketed for treating asthma,ibudilast (MN-166) is tested to treat acute respiratory distress syndrome (ARDS) associated with Covid-19.

Ibuprofen (Motrin) is an anti-inflammatory inhibitor targeting COX-1 and COX-2, of which is used for pain relief, fever reduction and for reducing swelling.

Ibutilide Fumarate is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm.

Idebenone

Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer.

Iloperidone (Fanapt)

Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. Imatinib is used to treat chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies.

Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist and is commonly used topically to treat warts on the skin of the genital and anal areas.

Indapamide (Lozol)

Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1).

Indomethacin (Indocid, Indocin)

Inhibitor of ATP-sensitive K+ channel activity in MIN 6 cells. Has also been shown to bind sulfonylurea receptors as well.

Inhibits bone resorption as a sodium salt and complexed with technetium Tc 99m for bone imaging. The monophosphonates are not active and the biphosphonates are used in disorders affecting the skeleton such as metastatic disease, asteoporosis and Paget's.

Inulin

Ipragliflozin (ASP1941) is a Novel Selective Sodium-Dependent Glucose Co-Transporter 2 Inhibitor, on Urinary Glucose Excretion in Healthy Subjects

Ipratropium bromide

Irsogladine maleate is a selective PDE4 inhibitor that facilitates gap junction intercellular communication through muscarinic acetylcholine receptor binding. It is a potent inhibitor of angiogenesis in wild-type and plasminogen activator-deficient mice.

Isepamicin

Isoliquiritigenin

Isoniazid is an antibacterial agent used primarily as a tuberculostatic.Target: AntibacterialIsoniazid is a prodrug and must be activated by a bacterial catalase-peroxidase enzyme that in M. tuberculosis is called KatG [1]. KatG couples the isonicotinic acyl with NADH to form isonicotinic acyl-NADH complex. This complex binds tightly to the enoyl-acyl carrier protein reductase known as InhA, thereby blocking the natural enoyl-AcpM substrate and the action of fatty acid synthase. This process inhibits the synthesis of mycolic acid, required for the mycobacterial cell wall. A range of radicals are produced by KatG activation of isoniazid, including nitric oxide, which has also been shown to be important in the action of another antimycobacterial prodrug PA-824 [2, 3]. Isoniazid is bactericidal to rapidly dividing mycobacteria, but is bacteriostatic if the mycobacteria are slow-growing [4].

Isoprenaline Hydrochloride is a non-selective beta-adrenergic agonist and structurally similar to adrenaline.

Isosorbide mononitrate(Isosorbide-5-mononitrate) is a nitrate-class compound used for angina pectoris; acts by dilating the blood vessels so as to reduce the blood pressure.

Isotretinoin(13-cis-Retinoic acid) is a medication used for the treatment of severe acne. It was first developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more.

Istradefylline(KW6002) is a very potent, selective and orally active adenosine A2A receptor antagonist(Ki=2.2 nM) in experimental models of Parkinson's disease.

Itraconazole (Sporanox)

Ketoprofen (Actron) is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively.

Ketorolac (Ketorolac tromethamine, Toradol) is a non-selective COX inhibitor with strong analgesic activity.

Ketotifen (fumarate) is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, which is used to prevent asthma attacks.

Kinetin (6-Furfuryladenine)

L-(-)-α-Methyldopa hydrate is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive.

L(+)-Rhamnose Monohydrate

Lactulose (Enulose)

Lafutidine

Lamotrigine(BW430C) is a novel anticonvulsant drug for inhibition of 5-HT and sodium channel.

Landiolol Hydrochloride

Lansoprazole(AG 1749) is a proton pump inhibitor which prevents the stomach from producing acid.

Lapatinib

L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

Leflunomide

Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class.

Letrozole(CGS-20267) is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant.

Leucovorin Calcium is a reduced folic acid.

Levamisole HCl(Ergamisol)

Levetiracetam

Levobupivacaine HCL

Levofloxacin (Levaquin)

Levonorgestrel(Levonelle)

Levosimendan

Levosulpiride is the (S)-enantiomer of sulpiride, which is a D2 receptor a antagonist, an atypical antipsychotic drug of the benzamide class.

Lexacalcitol

Lidocaine, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx.

Lincomycin HCl (Lincocin)

Liothyronine sodium (T3 Sodium sal) is the most potent form of thyroid hormone used to treat hypothyroidism and myxedema coma.

Lisinopril Dihydrate is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.

L-NAME is a nonselective inhibitor of nitric oxide synthetases (NOS) for nNOS (bovine), eNOS (human), and iNOS (murine), with Ki of 15 nM, 39 nM and 4.4 μM, respectively.

Lomefloxacin HCl (Maxaquin)

Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine.

Lomustine (CeeNU)

Loperamide HCl is an opioid-receptor agonist used as long-acting synthetic antidiarrheals.

Loratadine(SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.

Losartan is a potent, non peptide antagonist of the angiotensin II receptor type 1. This receptor initiates a signal cascade that causes vasoconstriction. Antagonism of this receptor in turn causes vasodilation by blocking the signal from angiotensin II.

Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

Loteprednol etabonate

Loxoprofen is a non-steroidal anti-inflammatory drug that is quickly converted to the trans-alcohol metabolite. It is similar to ibuprofen and naproxen, while also being a Cycloxygenase (COX) inhibitor.

L-Thyroxine

Lupus erythematosus suppressant as well as an antimalerial and antirheumatic.

Malotilate

Manidipine 2Hcl (CV-4093) is a dihydropyridine compound and a calcium channel blocker for Ca2+ current with IC50 of 2.6 nM.

Mecarbinate

Meclofenoxate hydrochloride, an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA), has been shown to improve memory, have a mentally stimulating effect, and improve general cognition.

Medetomidine hydrochloride is a potent and highly selective α2-AR adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). Shows greater selectivity over α1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- an

Meloxicam (Mobic)

Melphalan(Sarcolysin; L-PAM) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents; attaches the alkyl group to the guanine base of DNA.

Mestranol

Metformin HCl(Glucophage)

Methacycline HCl (Physiomycine)

Methimazole(Tapazole, Northyx) is an antithyroid medicine.

Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.

Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.

Methoxsalen (Oxsoralen)

Methylprednisolone

Metolazone (Zaroxolyn)

Metoprolol is a cardioselective β1-adrenergic blocking agent.

Mevastatin (Compactin; ML236B) inhibits HMGCR (HMG-CoA reductase) (Ki for acid form is 1 nM) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans.

Mexiletine hydrochloride is a non-selective voltage-gated sodium channel blocker; Class IB anti-arrhythmic compound.

Miglitol (Glyset)

Milbemycin oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of two natural products, milbemycin A3 and A4 (in ~70: 30 ratio). Moxidectin oxime, marketed as Interceptor, is used therapeutically for the prev

Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively.

Minoxidil(U 10858) is an antihypertensive vasodilator medication.

Miriplatin

Mirtazapine (Remeron, Avanza)

Mitotane (Lysodren)

Mitoxantrone HCl

Moguisteine is a novel peripheral non-narcotic antitussive drug.

Molsidomine is an orally active, long acting vasodilating drug, metabolized in the liver to the active metabolite linsidomine, which is an unstable compound that releases nitric oxide (NO) upon decay as the actual vasodilating compound.

Mometasone furoate

Monobenzone (Benoquin)

Moxonidine

Moxonidine hydrochloride

Mycophenolate mofetil is a prodrug for mycophenolic acid, a potent inhibitor of inosine monophosphate dehydrogenase (IC50 = 11 nM). Inhibition of this enzyme blocks de novo GTP generation as well as RNA and DNA synthesis in lymphocytes. In this way, mycop

Mycophenolic (Mycophenolate)

Nabumetone(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite inhibits the COX.

Naftopidil is an α-1-Adrenergic receptor antagonist and an antihypertensive.

Nalidixic acid (NegGram)

Nanchangmycin (dianemycin) is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for for mammals and plants.

Naphyrone (O-2482)

Naproxen is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.

Naproxen is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.

Naratriptan Hydrochloride is a triptan drug which is used for the treatment of migraine headaches.

Natamycin(Pimaricin)

Nateglinide is an insulin secretagog agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).

Nattokinase, Natto fermentation is a potent fibrinolytic enzyme. Nattokinase can break down blood clots by directly hydrolyzing fibrin and plasmin substrate. Nattokinase can be used for the research of cardiovascular diseases.

Nebivolol hydrochloride is a highly selective β1-adrenoceptor antagonist

Nedaplatin (Aqupla) is a derivative of cisplatin for inhibition of tumor colony forming units with IC50 of 28.5 μg/mL.

Nefiracetam is a nootropic of the racetam family. Nefiracetam is cognitive enhancer with an IC50 of approximately 150–200 μM for Ro 5-4864. This compound activates L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems. Nefiracetam di

Nefopanhydrochloride

Neostigmine Bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis.

Neostigmine Methyl Sulfate is a reversible acetylcholinesterase inhibitor. This compound blocks the breakdown of acetylcholine in the synaptic space, leading to prolonged signaling and thus increased muscle contractions.

Nepafenac

Nevirapine is a potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of HIV-1 infection and AIDS.