Aripiprazole

  Cat. No.:  DC9147  
Chemical Structure
129722-12-9
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Field of application
Aripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.
Cas No.: 129722-12-9
Chemical Name: 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Synonyms: OPC-14597; OPC 14597; OPC14597; Abilify; Abilitat; Abilify Discmelt.
SMILES: O=C1CCC2=CC=C(C=C2N1)OCCCCN1CCN(C2=CC=CC(Cl)=C2Cl)CC1
Formula: C23H27Cl2N3O2
M.Wt: 448.39
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Aripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.Aripiprazole is an atypical antipsychotic medication used for the treatment of schizophrenia. It has also recently received FDA approval for the treatment of acute manic and mixed episodes associated with bipolar disorder. Aripiprazole appears to mediate its antipsychotic effects primarily by partial agonism at the D2 receptor. In addition to partial agonist activity at the D2 receptor, aripiprazole is also a partial agonist at the 5-HT1A receptor, and like the other atypical antipsychotics, aripiprazole displays an antagonist profile at the 5-HT2A receptor. Aripiprazole has moderate affinity for histamine and alpha adrenergic receptors, and no appreciable affinity for cholinergic muscarinic receptors.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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