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ADCs Linker/Click Chemistry

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Cat. No. Product Name Field of Application Chemical Structure
DC28644 Propargyl-PEG6-NHS ester Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28645 Propargyl-PEG4-C2-NHS ester Propargyl-PEG4-C2-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28646 m-PEG6-Amine m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28647 Maleimido-tri(ethylene glycol)-propionic acid Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation.
DC28648 DBCO-PEG4-amine DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker).
DC28649 Mal-PEG2-acid Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin and its derivative cytotoxic molecule.
DC28650 N-Boc-N-bis(PEG4-OH) N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28651 m-PEG4-Ms m-PEG4-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28652 Azido-PEG6-NHS ester Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs.
DC28653 Azido-PEG9-acid Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28655 N-Boc-PEG2-bromide N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28656 N-Boc-PEG7-alcohol N-Boc-PEG7-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28663 m-PEG7-Ms m-PEG7-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28665 Hydroxy-PEG3-SS-PEG3-alcohol Hydroxy-PEG3-SS-PEG3-alcohol is also a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28666 m-PEG9-Amine m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28667 Azido-PEG5-acid Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as the conjugate CPT-APO (CPT: Camptothecin).
DC28668 Propargyl-PEG4-Br Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28698 DBCO-Sulfo-Link-biotin DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28699 Gemcitabine-O-Si(di-iso)-O-Mc Gemcitabine-O-Si(di-iso)-O-Mc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28719 Fmoc-NH-PEG5-CH2COOH Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28720 Fmoc-NH-PEG8-CH2COOH Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28861 Fmoc-Asp-NH2 Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC29011 NH-bis(C1-Boc) NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC).
DC29012 Mal-amido-(CH2COOH)2 Mal-amido-(CH2COOH)2, compound 7a, is a maleimidoethyl-containing intermediate for hydrophilic ADC linker.
DC29013 Tetraethylene glycol monotosylate Featured Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC29014 Mal-L-PA-NH-Boc Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC29015 BMPS BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC29017 Hydroxy-PEG3-(CH2)2-Boc Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196).
DC29018 N3-PEG3-CH2CH2-Boc N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
DC29020 Azido-PEG4-CH2-Boc Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

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