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Antibiotics and Antivirals

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Cat. No. Product Name Field of Application Chemical Structure
DC47594 Bictegravir Sodium Bictegravir (GS-9883) Sodium is a novel and potent inhibitor of HIV-1 integrase, specifically targets IN strand transfer activity with an IC50 of 7.5 nM.
DC47595 Zanamivir-Cholesterol Conjugate Zanamivir–cholesterol conjugate is a long-acting neuraminidase inhibitor with potent efficacy against drug-resistant influenza viruses.
DC47601 PMEDAP PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP has anti-murine cytomegalovirus (MCMV) activity. PMEDAP is a very potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality.
DC47602 Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.
DC47603 Tenofovir-C3-O-C15-CF3 ammonium Tenofovir-C3-O-C15-CF3 (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.
DC47604 GPS491 Featured GPS491 (EC50 = 0.47 μM) suppresses expression of the HIV-1 structural protein Gag and alters HIV-1 RNA accumulation, decreasing the abundance of RNAs encoding the structural proteins while increasing levels of viral RNAs encoding the regulatory proteins.
DC47605 HIV-1 inhibitor-9 HIV-1 inhibitor-9 is found to be potent inhibitor against the wild-type (WT) HIV-1 strain or multiple NNRTI-resistant strains at low nanomolar levels.
DC47606 Melliferone Melliferone is a triterpenoid found in Brazilian propolis.
DC47607 Antiviral agent 9 Antiviral agent 9 reaches a single-digit picomolar EC50 value (0.006 nM) against HIV-1 and nearly 300-fold higher selectivity index (SI) compared to tenofovir alafenamide fumarate (TAF).
DC47640 Fungicide5 Fungicide5 is a fungicide candidate targeting succinate dehydrogenase (Ki = 0.095 μM).
DC47641 Benzyl 2-hydroxy-6-methoxybenzoate Benzyl 2-hydroxy-6-methoxybenzoate shows the strongest antifungal effect, with IC50 of 25–26 μg/mL for both fungal strains.
DC47642 Antifungal agent 20 Antifungal agent 20 exhibits remarkable antifungal activity against Colletotrichum gloeosprioides, Rhizoctonia solani, Phytophthora nicotianae var. nicotianae, Diplodia pinea, Colletotrichum acutatum, and Fusarium oxysporum f. sp. niveum.
DC47643 Phenazine-1-carboxylic acid Phenazine-1-carboxylic acid exhibits strong antifungal activity against phytopathogenic fungi.
DC47644 5-epi-Jinkoheremol 5-epi-Jinkoheremol exhibits more potent fungicidal activity than validamycin.
DC47645 Antifungal agent 18 Antifungal agent 18 is a novel antifungal agent for the treatment of fungal infection.
DC47646 Antifungal agent 15 Antifungal agent 15 has the most potent activity with EC50 values of 0.52 and 0.50 μg/mL against S. sclerotiorum and B. cinerea, respectively.
DC47647 Antifungal agent 14 Antifungal agent 14 exhibits broad-spectrum activity against the fungal strains with excellent minimum inhibitory concentration values.
DC47648 Nystatin A3 Nystatin A3, produced by Streptomyces noursei, a biologically active component of nystatin complex. Antibiotic activity
DC47649 Fungicide4 Fungicide4 shows the high activity against the P. infestans strain.
DC47650 Debneyol Debneyol exhibits more potent fungicidal activity than validamycin.
DC47651 Antifungal agent 13 Antifungal agent 13 exhibits remarkable antifungal activity against Sclerotinia sclerotiorum with an EC50 value of 1.25 mg/L.
DC47652 Antifungal agent 19 Antifungal agent 19 shows the potent antifungal activity (EC50 = 0.72 μM).
DC47653 Antifungal agent 17 Antifungal agent 17 exhibits excellent antifungal properties against B. cinerea with an EC50 value of 2.86 μg/mL.
DC47654 Antifungal agent 16 Antifungal agent 16 displays considerable antibacterial activity and superior antifungal activity with reference to ciprofloxacin and fluconazole, respectively.
DC47655 Antifungal agent 12 Antifungal agent 12 is a novel fluconazole-based compound with promising antifungal activities.
DC47656 Antifungal agent 11 Antifungal agent 11 shows the promising antifungal activity.
DC47663 WIN 54954 WIN 54954 is a broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections.
DC47723 Decamethoxine Decamethoxine (Septefril) is a cationic gemini surfactant. Decamethoxine exhibits strong bactericidal and fungicidal effects. Decamethoxine modifies the permeability of the microbial cell membrane, resulting in the destruction and death of diverse microorganisms.
DC47724 Hikizimycin Hikizimycin is a potent anthelmintic and antibacterial natural product.
DC47725 ARX-1796 ARX-1796 (AV-006), an Avibactam prodrug, is an orally bioavailable β-lactamase inhibitor. Avibactam has a spectrum of inhibition of class A and C β-lactamases, including ESBLs, AmpC and Klebsiella pneumoniae carbapenemase (KPC) enzymes.

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