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Antibiotics and Antivirals

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Cat. No. Product Name Field of Application Chemical Structure
DC47726 Antistaphylococcal agent 3 Antistaphylococcal agent 3 is an antistaphylococcal therapeutic agent.
DC47727 Antistaphylococcal agent 2 Antistaphylococcal agent 2 is an antistaphylococcal therapeutic agent.
DC47728 Antistaphylococcal agent 1 Antistaphylococcal agent 1 is an antistaphylococcal therapeutic agent.
DC47729 Antibacterial agent 28 Antibacterial agent 28 is a potential antibacterial candidate for combating MRSA infections (MICs = 0.5–2 μg/mL).
DC47730 Antitubercular agent-10 Antitubercular agent-10 shows potent antitubercular activity with a MIC value of 30 nM.
DC47731 Antibacterial agent 30 Antibacterial agent 30 demonstrates excellent in vitro activity against Xoo with EC50 value of 1.9 μg/mL.
DC47732 Antibacterial agent 31 Antibacterial agent 31 shows the antibacterial activity against rice bacterial leaf streak.
DC47733 Antitubercular agent-9 Antitubercular agent-9 shows effective antitubercular activity with a MIC value of 1.03-2.32 μM.
DC47734 Brodimoprim Brodimoprim (Ro 10-5970), a trimethoprim analogue, is an orally active dihydrofolate reductase inhibitor. Brodimoprim is highly active against a broad spectrum of gram-negative and gram-positive bacteria.
DC47735 Uvaretin A mixture of uvaretin and isouvaretin exhibits significant antibacterial activity against B. subtilis (EC50 8.7 μM) and S. epidermidis (IC50 7.9 μM).
DC47736 Targeting the bacterial sliding clamp peptide 46 Targeting the bacterial sliding clamp peptide 46 is a short peptide targeting the bacterial sliding clamp(SC), inhibiting SC-dependent DNA synthesis.
DC47737 Isouvaretin A mixture of uvaretin and isouvaretin exhibits significant antibacterial activity against B. subtilis (EC50 8.7 μM) and S. epidermidis (IC50 7.9 μM).
DC47738 (8′α,9′β-Dihydroxy)-3-farnesylindole (8'α,9'β-Dihydroxy)-3-farnesylindole shows strong inhibitory activity (EC50 9.8 μM) against B. subtilis.
DC47739 JPD447 JPD447, a MAC-0547630 derivative, is a novel class of UppS inhibitor to potentiate β-lactam antibiotics.
DC47740 Urease-IN-1 Urease-IN-1 is an urease inhibitor with an IC50 value of 2.21 ± 0.45 µM.
DC47741 LpxA-IN-1 LpxA-IN-1 is a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor (IC50 2 nM) with activity against Pseudomonas aeruginosa (MIC 8 μg/mL).
DC47742 Antibacterial agent 63 Antibacterial agent 63, a conjugate of aztreonam to a siderophore mimetic, shows activity against gram-negative bacteria.
DC47743 Anti gram-positive/negative bacteria agent 1 Anti gram-positive/negative bacteria agent 1 is an antibiotic conjugate with an artificial MECAM-based siderophore.
DC47744 Antibacterial agent 62 Antibacterial agent 62 is a novel redox cycling antituberculosis chemotype with potent bactericidal activity against growing and nutrient-starved phenotypically drug-resistant nongrowing bacteria.
DC47745 NBTIs-IN-4 NBTIs-IN-4 demonstrates potent antibacterial activity against diverse Gram-positive pathogens, inhibition of both DNA gyrase and topoisomerase IV, a low frequency of resistance.
DC47746 MDP1 MDP1, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa.
DC47747 MDP1 acetate MDP1 acetate, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 acetate has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa.
DC47753 Lithium Chloride Lithium Chloride inhibits the replication of type 1 and type 2 Herpes simplex virus at concentrations which permitted host cell replication. Lithium chloride also prevents glucocorticoid-induced osteonecrosis of femoral heads and strengthens mesenchymal stem cell activity in rats.
DC47755 Bleomycin A5 hydrochloride Bleomycin A5 hydrochloride is an anti-neoplastic glycoprotein antibiotic. Bleomycin A5 suppresses Drp1‑mediated mitochondrial fission and induces apoptosis in human nasal polyp‑derived fibroblasts.
DC58060 VV116 (non-deuterated) Featured non-deuterated form of VV116.VV116 is an oral drug candidate of nucleoside analog against SARS-CoV-2.
DC47865 β-Rubromycin β-Rubromycin is a potent and selective inhibitor of human immunodeficiency virus-1 (HIV-1) RNA-directed DNA polymeras (reverse transcriptase). β-Rubromycin is a class of quinone antibacterials.
DC47866 β-Lactamase-IN-6 β-Lactamase-IN-6 is a β-Lactamase inhibitor that shows high antibacetrial activity.
DC47874 Vanillinbananin Vanillinbananin is an effective inhibitor of the ATPase activity of the SARS Coronavirus helicase with an IC50 value of 0.68 μM.
DC47891 T-2307 T-2307, an arylamidine, has antifungal activities in vitro and in vivo. T-2307 exhibits broad-spectrum activity against clinically significant pathogens, including Candida species (MIC range, 0.00025 to 0.0078 μg/ml), Cryptococcus neoformans (MIC range, 0.0039 to 0.0625 μg/ml), and Aspergillus species (MIC range, 0.0156 to 4 μg/mL) .
DC47906 SARS-CoV-2-IN-10 SARS-CoV-2-IN-10 is a potent and nontoxic inhibitor of SARS-CoV-2 3CL protease (3CLpro) with an IC50 and EC50 of 0.13 and 1.03 nM, respectively. SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication, is an attractive target for therapeutic intervention. SARS-CoV-2-IN-11 may lead to the emergence of effective SARS-CoV-2-specific antivirals.

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