DC47111 |
Ecubectedin |
Ecubectedin is a derivative. Ecteinascidins is a family of tetrahydroisoquinoline alkaloids with wide range of antitumor and antimicrobial activities. |
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DC47119 |
β-Lactamase-IN-5 |
β-Lactamase-IN-5 is a β-lactamase inhibitor extracted from patent WO2013149121A1, compound 720. β-Lactamase-IN-5 can be used for the research of bacterial infections. |
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DC47120 |
β-Lactamase-IN-4 |
β-Lactamase-IN-4 is a β-lactamase inhibitor extracted from patent WO2013149121A1, compound 708. β-Lactamase-IN-4 can be used for the research of bacterial infections. |
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DC47160 |
Antibacterial agent 58 |
Antibacterial agent 58, an antibacterial agent, significantly lowers MIC value of antibacterial agent Ceftazidime. |
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DC47174 |
Temocillin disodium |
Temocillin disodium, a 6-α-methoxy penicillin, possesses antibacterial activity. |
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DC47186 |
Ledaborbactam |
Iedaborbactam, as a beta-lactamase inhibitor (WO2015191907, Example 62), can be used for the research of bacterial infections. |
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DC47202 |
FPI-1523 sodium |
FPI-1523 sodium, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 sodium also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 sodium exhibits considerable antimicrobial activity. |
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DC47203 |
FPI-1523 |
FPI-1523, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 exhibits considerable antimicrobial activity. |
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DC47221 |
Ledaborbactam etzadroxil |
Ledaborbactam etzadroxil (VNRX-7145) is an orally active Ambler class A, C, and D β-lactamase enzymes inhibitor. |
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DC47231 |
Dup-721
Featured
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DuP-721 is a broad spectrum and orally active antibacterial agent against a variety of clinically susceptible and resistant bacteria, especially M. tuberculosis. |
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DC47253 |
Contezolid acefosamil sodium |
Contezolid acefosamil sodium (MRX-4), a new and orally active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid acefosamil sodium (MRX-4) markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI). |
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DC47303 |
Essential oils, Melaleuca alternifolia |
Essential oils, Melaleuca alternifolia is extracted from the leaves of Melaleuca alternifolia, has bactericidal and anti-inflammatory activies. |
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DC47723 |
Decamethoxine |
Decamethoxine (Septefril) is a cationic gemini surfactant. Decamethoxine exhibits strong bactericidal and fungicidal effects. Decamethoxine modifies the permeability of the microbial cell membrane, resulting in the destruction and death of diverse microorganisms. |
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DC47724 |
Hikizimycin |
Hikizimycin is a potent anthelmintic and antibacterial natural product. |
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DC47725 |
ARX-1796 |
ARX-1796 (AV-006), an Avibactam prodrug, is an orally bioavailable β-lactamase inhibitor. Avibactam has a spectrum of inhibition of class A and C β-lactamases, including ESBLs, AmpC and Klebsiella pneumoniae carbapenemase (KPC) enzymes. |
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DC47726 |
Antistaphylococcal agent 3 |
Antistaphylococcal agent 3 is an antistaphylococcal therapeutic agent. |
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DC47727 |
Antistaphylococcal agent 2 |
Antistaphylococcal agent 2 is an antistaphylococcal therapeutic agent. |
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DC47728 |
Antistaphylococcal agent 1 |
Antistaphylococcal agent 1 is an antistaphylococcal therapeutic agent. |
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DC47729 |
Antibacterial agent 28 |
Antibacterial agent 28 is a potential antibacterial candidate for combating MRSA infections (MICs = 0.5–2 μg/mL). |
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DC47730 |
Antitubercular agent-10 |
Antitubercular agent-10 shows potent antitubercular activity with a MIC value of 30 nM. |
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DC47731 |
Antibacterial agent 30 |
Antibacterial agent 30 demonstrates excellent in vitro activity against Xoo with EC50 value of 1.9 μg/mL. |
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DC47732 |
Antibacterial agent 31 |
Antibacterial agent 31 shows the antibacterial activity against rice bacterial leaf streak. |
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DC47733 |
Antitubercular agent-9 |
Antitubercular agent-9 shows effective antitubercular activity with a MIC value of 1.03-2.32 μM. |
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DC47734 |
Brodimoprim |
Brodimoprim (Ro 10-5970), a trimethoprim analogue, is an orally active dihydrofolate reductase inhibitor. Brodimoprim is highly active against a broad spectrum of gram-negative and gram-positive bacteria. |
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DC47735 |
Uvaretin |
A mixture of uvaretin and isouvaretin exhibits significant antibacterial activity against B. subtilis (EC50 8.7 μM) and S. epidermidis (IC50 7.9 μM).
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DC47736 |
Targeting the bacterial sliding clamp peptide 46 |
Targeting the bacterial sliding clamp peptide 46 is a short peptide targeting the bacterial sliding clamp(SC), inhibiting SC-dependent DNA synthesis. |
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DC47737 |
Isouvaretin |
A mixture of uvaretin and isouvaretin exhibits significant antibacterial activity against B. subtilis (EC50 8.7 μM) and S. epidermidis (IC50 7.9 μM).
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DC47738 |
(8′α,9′β-Dihydroxy)-3-farnesylindole |
(8'α,9'β-Dihydroxy)-3-farnesylindole shows strong inhibitory activity (EC50 9.8 μM) against B. subtilis. |
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DC47739 |
JPD447 |
JPD447, a MAC-0547630 derivative, is a novel class of UppS inhibitor to potentiate β-lactam antibiotics. |
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DC47740 |
Urease-IN-1 |
Urease-IN-1 is an urease inhibitor with an IC50 value of 2.21 ± 0.45 µM. |
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