| DC48678 |
Colistin adjuvant-1 |
Colistin adjuvant-1 is a colistin adjuvant, shows increased colistin potentiation activity against Gram-negative bacteria. Colistin adjuvant-1 inhibits NF-κB with an IC50 of 0.209 μM. |
|
| DC48683 |
OX11 |
OX11 is a selective inhibitor of S. pneumoniae, P. aeruginosa, and E. coli bacterial strains. |
|
| DC48684 |
Antibacterial agent 66 |
Antibacterial agent 66 (Compound 6q), a trifluoromethylpyridine 1,3,4-oxadiazole derivative, shows activity against Xanthomonas oryzae pv. oryzae (Xoo) with an EC50 value of 7.2 μg/mL. |
|
| DC48744 |
Antimicrobial photosensitizer-1 |
Antimicrobial photosensitizer-1 is a promising candidate as the antimicrobial photosensitizer for combating pathogenic microorganism infections. Antimicrobial photosensitizer-1 exhibits an impressive antimicrobial efficacy in S. aureus-infected mice wounds. |
|
| DC48748 |
Antibacterial agent 72 |
Antibacterial agent 72 displays the antibacterial activities by targeting the bacterial membrane. |
|
| DC48756 |
Antibacterial synergist 1 |
Antibacterial synergist 1 (compound 20P) is a bacterial biofilm inhibitor. Antibacterial synergist 1 inhibits the production of pyocyanin and biofilm formation with IC50s of 8.6 and 4.5 μM, respectively. Antibacterial synergist 1 has the potential for the research of P. aeruginosa infections. |
|
| DC48765 |
Asperglaucin B |
Asperglaucin B is an alkylated salicylaldehyde derivative from the fungus Aspergillus chevalieri SQ-8, with antibacterial activities. Asperglaucin B displays potent antibacterial activities against two plant pathogens Pseudomonas syringae pv actinidae (Psa) and Bacillus cereus, with an MIC value of 6.25 μM. |
|
| DC48766 |
Asperglaucin A |
Asperglaucin A represents an unusual phthalide-like derivative. Asperglaucin A exhibits potent antibacterial activities against two plant pathogens Pseudomonas syringae pv actinidae (Psa) and Bacillus cereus, with an MIC value of 6.25 μM. |
|
| DC48781 |
Saccharothrixin F |
Saccharothrixin F is a highly oxygenated saccharothrixin, with antibacterial and anti-inflammatory activities. |
|
| DC48785 |
(R,R)-BAY-Y 3118 |
(R,R)-BAY-Y 3118 is the R-enantiomer of BAY-Y 3118. (R,R)-BAY-Y 3118 shows weak bactericidal activity. |
|
| DC48842 |
Bipolamine G |
Bipolamine G is an antibacterial polyketide alkaloid. |
|
| DC48878 |
Iboxamycin |
Iboxamycin is a potent antibiotic candidate bearing a fused bicyclic amino acid residue. Iboxamycin is orally bioavailable, safe and effective in treating both Gram-positive and Gram-negative bacterial infections in mice. |
|
| DC48884 |
N-Decyl-N,N-dimethyldecan-1-aminium chloride |
N-Decyl-N,N-dimethyldecan-1-aminium chloride (Didecyldimethylammonium chloride) is a dialkyl-quaternary ammonium compound that is used in numerous products for its bactericidal, virucidal and fungicidal properties. |
|
| DC48924 |
Fenticonazole |
Fenticonazole is an imidazole derivative with antibacterial and antifungal activity. Fenticonazole has the potential for the research of mixed vaginitis. |
|
| DC48962 |
DATPT |
DATPT is a 12WLVSKF17 peptide-mimetic molecule. DATPT blocks the SNX9-p47phox interaction in the endosome and suppresses reactive oxygen species and inflammatory cytokine production. DATPT with anti-inflammatory and antibacterial functions has the potential for the research of sepsis. |
|
| DC48997 |
Saccharothrixin K |
Saccharothrixin K, a glycosylated saccharothrixin, shows moderate inhibition against Helicobacter pylori G27, H. pylori 159, and Staphylococcus aureus ATCC25923 with MIC values of 16 μg/mL. |
|
| DC49077 |
Aszonapyrone A |
Aszonapyrone A is a metabolite produced by Aspergillus zonatus. |
|
| DC49240 |
Galloyl-bis-HHDP glucose |
Galloyl-bis-HHDP glucose (HeT) is an ellagitannin, which exhibits phytoprotective effects against Pseudomonas viridiflava. |
|
| DC49367 |
(S)-1-(4-Hydroxyphenyl)ethane-1,2-diol |
(S)-1-(4-Hydroxyphenyl)ethane-1,2-diol is an active constituent of the aerial parts of Angelica sinensis. (S)-1-(4-Hydroxyphenyl)ethane-1,2-diol significantly inhibits the growth of Aeromonas hydrophila. Anticoagulative and antibiotic activities. |
|
| DC49410 |
Indolicidin acetate |
Indolicidin acetate is a potent antimicrobial peptide purified from the cytoplasmic granules of bovine neutrophils. |
|
| DC49418 |
TNP-2198 |
TNP-2198 is a potent and orally bioavailable dual-targeted antibacterial agent. TNP-2198 has potent activity against microaerophilic and anaerobic bacterial pathogens. |
|
| DC49419 |
Antibacterial agent 68 |
Antibacterial agent 68 (compound 4d) is an antibacterial agent against drug-resistant Escherichia coli. Antibacterial agent 68 has low cytotoxicity and exerts strong antibacterial activities against multidrug-resistant Escherichia coli at low concentrations as 0.007 mM. |
|
| DC49420 |
MsbA-IN-2 |
MsbA-IN-2 (compound 12) is a potent lipopolysaccharide transporter MsbA inhibitor with an IC50 of 2 nM for E. coli MsbA. |
|
| DC49421 |
17-Hydroxyventuricidin A |
17-Hydroxyventuricidin A (YP-02259L-C) is an antimicrobial compound.17-Hydroxyventuricidin A inhibits the growth of the two tested filamentous fungi (Verticillium dahlia and Fusarium sp.) and of Candida tropicalis R2 CIP203. |
|
| DC49422 |
Sulfadiazine-13C6 |
Sulfadiazine-13C6 is a labeled Sulfadiazine. Sulfadiazine is a sulfonamide antibiotic with antimalarial activity.
|
|
| DC49423 |
Desfuroylceftiofur |
Desfuroylceftiofur is an active metabolite of Ceftiofur which is a broad-spectrum cephalosporin antibiotic. Desfuroylceftiofur is active against gram-positive and gram-negative bacteria. |
|
| DC49424 |
Octanal |
Octanal is an aromatic aldehyde, with antioxidant and antimicrobial activities. Octanal shows cytotoxicity against Hela cells. |
|
| DC49425 |
Curvulamine A |
Curvulamine A, an antibacterial alkaloid, shows potent antibacterial activity. |
|
| DC49426 |
2-Hydroxydocosanoic acid |
2-Hydroxydocosanoic acid has antioxidant, cholinesterase inhibitory, and antimicrobial activities. |
|
| DC49427 |
RmlA-IN-1 |
RmlA-IN-1 (Compound 8a) is a potent inhibitor of glucose-1-phosphate thymidylyltransferase (RmlA) with an IC50 of 0.073 μM. RmlA-IN-1 influences monosaccharide l-Rhamnose biosynthetic pathway. RmlA-IN-1 affects bacterial cell wall permeability. |
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