| DC11273 |
Murepavadin (POL7080)
Featured
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Murepavadin is a novel class of highly specific outer membrane protein targeting antibiotic to treat resistant Pseudomonas infections. |
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| DCAPI1293 |
Nanchangmycin |
Nanchangmycin (dianemycin) is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for for mammals and plants. |
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| DC11016 |
NOSO-502 |
NOSO-502 (NOSO502) is a novel inhibitor of bacterial translation, has MIC values of 0.5-4 ug/ml against standard Enterobacteriaceae strains and carbapenem-resistant Enterobacteriaceae (CRE) isolates that produce KPC, AmpC, or OXA enzymes and metallo-β-lactamases. |
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| DC7625 |
PA-824(Pretomanid)
Featured
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PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2. |
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| DC9723 |
PBTZ169
Featured
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PBTZ169 is a decaprenyl-phosphoribose-epimerase (DprE1) inhibitor. |
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| DC10441 |
Relebactam
Featured
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Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases [ESBLs] and KPC) and class C (AmpC) enzymes. |
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| DC4148 |
Retapamulin |
Retapamulin is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with Kd of 3 nM. |
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| DCAPI1325 |
Rifabutin (Mycobutin) |
Rifabutin (Mycobutin) |
|
| DC8032 |
Solithromycin
Featured
|
Solithromycin is a novel ketolide antibiotic. |
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| DC10733 |
Sutezolid (PNU-100480)
Featured
|
Sutezolid (PNU-100480) is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis. |
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| DC7940 |
TBA-354 |
TBA-354 is a potent anti-tuberculosis compound; maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates. |
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| DC8336 |
Tizoxanide
Featured
|
Tizoxanide is a potent inhibitor of hepatitis B virus and hepatitis C virus. |
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| DC10265 |
Tubercidin
Featured
|
Tubercidin, an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities. |
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| DC10286 |
Vaborbactam
Featured
|
Vaborbactam is a cyclic boronic acid pharmacophore β-lactamase inhibitor. |
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| DC8115 |
Vancomycin hydrochloride
Featured
|
Vancomycin hydrochloride in stock,price: 500 USD/100mg. 0 |
|
| DC10497 |
VXc-486
Featured
|
VXc-486 is active against drug-resistant isolates, has bactericidal activity, and kills intracellular and dormant M. tuberculosis bacteria in a low-oxygen environment. |
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| DC7532 |
Walrycin-B
Featured
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Walrycin B is a novel antibacterial compound specifically targeting the essential WalR response regulator. |
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| DC11277 |
Zoliflodacin(AZD0914)
Featured
|
Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. |
|
| DC11102 |
Taniborbactam |
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|
| DC10109 |
Q203
Featured
|
Q203 is a promising new clinical candidate for the treatment of tuberculosis. |
|
| DC28080 |
Ro 20-0657/000
Featured
|
Ro 20-0657/000 is a metabolite of Trimethoprim. Trimethoprim is a dihydrofolate reductase inhibitor, used as an antibacterial agent in human and veterinary medicine. |
|
| DC28108 |
Flurofamide |
Flurofamide is a potent bacterial urease inhibitor with potential clinical utility in the treatment of infection induced urinary stones. |
|
| DC28191 |
Cefathiamidine |
Cefathiamidine is a first-generation cephalosporin antibacterial agent and is used to treat infections caused by susceptible bacteria. Cefathiamidine exhibits a wide spectrum of antimicrobial activity against bacteria. Cefathiamidine is used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis. |
|
| DC28215 |
A40926
Featured
|
A40926, the precursor of Dalbavancin, is a second-generation glycopeptide antibiotic. A40926 inhibits gram-positive bacteria, and is very active against Neisseria gonorrhoeae. |
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| DC28229 |
Cefodizime
Featured
|
Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts. |
|
| DC28258 |
BM635 hydrochloride |
BM635 hydrochloride is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 hydrochloride has an MIC50 of 0.08 μM against M.tuberculosis H37Rv. BM635 hydrochloride doubles the in vivo exposure with respect to the free base BM635. |
|
| DC28259 |
BM635 mesylate |
BM635 mesylate is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 mesylate has a MIC50 of 0.6 μM against M. tuberculosis H37Rv. BM635 mesylate significantly improves the bioavailability compared to free-base BM635. |
|
| DC28282 |
(3R,4R)-A2-32-01 |
(3R,4R)-A2-32-01 (compound 2), an anti-virulence drug, is a specific caseinolytic protein proteases (ClpP) inhibitor with an EC50 of 4.5 μM, and shows a tolerable cytotoxicity. |
|
| DC28403 |
Psicofuranine |
Psicofuramine a nucleoside antibiotic and has the inhibition of xanthosine 5'-phosphate aminase. Psicofuranine also specifically inhibits GMP synthase, and interrupts parasite growth. Psicofuranine exhibits a dose-dependent inhibition of P. falciparum growth. |
|
| DC28542 |
Ramoplanin |
Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic derived from the Actinoplanes spp with with activity against gram-positive bacteria. |
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