| DC40116 |
Demecycline |
Demecycline, a tetracycline antibiotic, is the C6-demethylated derivative of Tetracycline against bacterial infections including pneumonia and other respiratory tract infections.
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| DC40138 |
Chrysomycin B |
Chrysomycin B is an antibiotic isolated from a strain of Streptomyces. Chrysomycin B causes DNA damage in the human lung adenocarcinoma A549 cell line and inhibits topoisomerase II. Chrysomycin B suppresses the growth of transplantable tumors in mice. |
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| DC40217 |
Metronidazole acetic acid
Featured
|
Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa. |
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| DC40219 |
VU0420373 |
VU0420373 is a potent heme sensor system (HssRS) activator with an EC50 of 10.7 μM and a pEC50 of 4.97. VU0420373 induces heme biosynthesis, and is toxic to fermenting S. aureus. |
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| DC40220 |
Bisdionin C |
Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively. |
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| DC40243 |
N-(Hydroxymethyl)nicotinamide |
N-(Hydroxymethyl)nicotinamide is an antimicrobic agent. |
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| DC40253 |
12-Oxo phytodienoic acid |
12-Oxo phytodienoic acid is a biologically active, immediate precursor of 7-epi jasmonic acid. 12-Oxo phytodienoic acid appears to play an independent role in mediating resistance to pathogens and pests. |
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| DC40267 |
Alafosfalin |
Alafosfalin is an inhibitor of cell wall biosynthesis. Alafosfalin is a phosphonodipeptide with antibacterial properties. |
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| DC40271 |
N-Acetyltyramine |
N-Acetyltyramine is a quorum-sensing inhibitor (QSI) compound produced by V. alginolyticus M3-10. N-Acetyltyramine is capable of inhibiting the QS of C. violaceum ATCC 12472. N-acetyltyramine reverses resistance in Doxorubicin-resistant leukemia P388 cells. |
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| DC40279 |
Difloxacin |
Difloxacin is an antimicrobial agent. |
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| DC40280 |
Difloxacin D3 hydrochloride trihydrate |
Difloxacin D3 hydrochloride trihydrate is a deuterium labeled Difloxacin. Difloxacin is an antimicrobial agent. |
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| DC40327 |
N-Octanoyl-L-homoserine lactone |
N-octanoyl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. N-octanoyl-L-Homoserine lactone can be used for the infection prevention and regulation of virulence in general and in cystic fibro. |
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| DC40342 |
Actinomycin X2 |
Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection. |
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| DC40347 |
2-Mercaptopyridine N-oxide sodium |
2-Mercaptopyridine N-oxide sodium has bactericidal effect and is against a standard strain of Mycobacterium tuberculosis H37Rv (ATCC 27294) with MIC90 of 7.20 μM. 2-Mercaptopyridine N-oxide sodium and its complex with iron, gallium, and bismuth have good anti-M. tuberculosis activity. 2-Mercaptopyridine N-oxide sodium has potential for the treatment of tuberculosis. |
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| DC40365 |
Tirandamycin A |
Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties. |
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| DC40382 |
Benzyldodecyldimethylammonium chloride dihydrate |
Benzyldodecyldimethylammonium chloride dihydrate is a quaternary ammonium compound (QAC) and can be used as a biocide to target antibiotic-resistant bacteria, such as methicillin-resistant?Staphylococcus aureus?(MRSA), multidrug-resistant (MDR)?P. aeruginosa?et. al. Benzyldodecyldimethylammonium chloride dihydrate, an antimicrobial agent, bacteriostatic or bactericidal properties depending on the concentration. |
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| DC40386 |
Tylvalosin tartrate |
Tylvalosin tartrate (Acetylisovaleryltylosin tartrate) is a macrolide antibiotic that can against Gram-positive bacteria. |
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| DC40389 |
2'-Hydroxy-2-methoxychalcone |
2'-Hydroxy-2-methoxychalcone (compound 3b) is a synthetic chalcone, with antimicrobial activity. |
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| DC40391 |
Dehydroacetic acid sodium |
Dehydroacetic acid sodium, a pyrone derivative acts as an antibacterial and antifungal agent. Dehydroacetic acid possess phytotoxic activity. |
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| DC40399 |
MRL-494 hydrochloride |
MRL-494 hydrochloride, an antibacterial agent, is a inhibitor of β-barrel assembly machine A (BamA) impervious to efflux and the outer membrane permeability barrier. MRL-494 hydrochloride can inhibits Gram-positive (MIC of 12.5 μM for Staphylococcus aureus COL) and Gram-negative (MIC of 25 μM for E. coli JCM158) bacterias. |
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| DC40400 |
SPR206 acetate |
SPR206 acetate is a polymyxin analog with antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. SPR206 acetate has an anti-bacterial infection effect by interacting with the bacterium’s outer membrane. The MIC values of SPR206 acetate against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L. |
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| DC40418 |
Bafilomycin C1 |
Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H+-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi. Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC). |
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| DC40486 |
Mequindox |
Mequindox is an antimicrobial agent. Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice. |
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| DC40493 |
Cefpodoxime proxetil impurity B |
Cefpodoxime proxetil impurity B is an impurity of Cefpodoxime proxetil. Cefpodoxime Proxetil is a first oral and broad spectrum antibiotic that belongs to the third generation of cephalosporin.
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|
| DC40646 |
Senecivernine |
Senecivernine, a pyrrolizidine alkaloid isolated from Senecio species, exhibits a weakly mutagenic activity. |
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| DC40647 |
Neoabietic acid |
Neoabietic acid is an abietic-type acid isolated from the oleoresin and rosin of Pinus palustris. Neoabietic acid is highly susceptible to mineral acid. Neoabietic acid has antibacterial activity in vitro. |
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| DC40714 |
N-Tetradecanoyl-L-homoserine lactone |
N-Tetradecanoyl-L-homoserine lactone is a major chemical modulators of within and between cell communication and regulation. N-Tetradecanoyl-L-homoserine lactone can be used for the study of quorum sensing in vitro. |
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| DC40718 |
Pyrrolnitrin
Featured
|
Pyrrolnitrin is an antibiotic isolated from Pseudomonas pyrrocinia. Pyrrolnitrin shows a broad spectrum of antibiotic activity against fungi, yeast and gram-positive bacteria. |
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| DC40857 |
N-Acetylmuramic acid-alkyne |
N-Acetylmuramic acid-alkyne is a derivative of N-acetylmuramic acid (NAM) component of bacterial peptidoglycans. N-Acetylmuramic acid-alkyne incorporates into bacterial peptidoglycans during biosynthesis. N-Acetylmuramic acid-alkyne can be used for fluorescent labeling of peptidoglycans when 'click'-conjugated to a fluorescent dye. |
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| DC40886 |
Oxazosulfyl |
Oxazosulfyl is a potent agricultural fungicide. Oxazosulfyl can be used as an insecticide against major rice pests. |
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