| DC44823 |
Thiomandelic acid |
Thiomandelic acid is a broad spectrum inhibitor of Zinc -lactamases. |
|
| DC44824 |
LpxH-IN-AZ1 |
LpxH-IN-AZ1, a sulfonyl piperazine compound, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. LpxH-IN-AZ1 is a potent inhibitor of Klebsiella pneumoniae LpxH with IC50 of 0.36 μM . |
|
| DC45344 |
Multicaulisin |
Multicaulisin, a new Diels-Alder type adduct from Morus multicaulis roots, potently effects against Staphylococcus aureus (MRSA) isolates. Multicaulisin is an antibacterial drug and has the potential for MRSA infections research. |
|
| DC45397 |
4aα,7α,7aα-Nepetalactone |
4aα,7α,7aα-Nepetalactone exhibits antibacterial activity, and inhibits Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi and Enterococcus faecalis. |
|
| DC45412 |
(-)-Corypalmine |
(-)-Corypalmine (Discretinine), an alkaloid that could be isolated from the stem of Guatteriopsis friesiana, possesses antimicrobial activity. |
|
| DC45423 |
3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone |
3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a natural compound that could be isolated from G. lucidum with antimycobacterial activity. |
|
| DC45450 |
Haplopine |
Haplopine possesses photo-activated antimicrobial and DNA binding activities. |
|
| DC45458 |
Dehydrotomatine |
Dehydrotomatine is one of major steroidal glycoalkaloids (SGAs) that accumulate in the mature green fruits, leaves and flowers of tomato (Solanum lycopersicum). Dehydrotomatine is against bacteria, fungi, insects and animals. |
|
| DC45459 |
Bismuth subcarbonate |
Bismuth subcarbonate (Bismuth carbonate oxide) is a typical Bi-based semiconductor that is widely applied as antibacterial, sensors, super capacitors, and photocatalysts. Bismuth subcarbonate protects the gastric ulcer from further erosion by gastric acid. |
|
| DC45477 |
(1R)-α-Pinene |
(1R)-α-Pinene is a volatile monoterpene with antimicrobial activities. (1R)-α-Pinene reduces Bacillus cereus population growth, and exhibits repellent effects. |
|
| DC45505 |
Bis(dihydrochelerythrinyl)amine |
Bis(dihydrochelerythrinyl)amine possesses anti-bacteria activity. |
|
| DC45515 |
Methyl caffeate |
Methyl caffeate, an antimicrobial agent, shows moderate antimicrobial and prominent antimycobacterial activities. Methyl caffeate also exhibits α-glucosidase inhibition activity, oxidative stress inhibiting activity, anti-platelet activity, antiproliferative activity in cervix adenocarcinoma and anticancer activity in lung and leukmia cell lines. |
|
| DC45533 |
Prodigiosin hydrochloride |
Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties. |
|
| DC45534 |
(R)-Eucomol |
(R)-Eucomol, a flavonoid derivative, displays marginal antibacterial activity. (R)-Eucomol shows cytotoxic activity against KB and P-388 cells. |
|
| DC45535 |
Ascr#18 |
Ascr#18, an ascaroside, is a hormone of nematodes. Ascr#18 is expressed during nematode development. Ascr#18 increases resistance in Arabidopsis, tomato, potato and barley to viral, bacterial, oomycete, fungal and nematode infections. |
|
| DC45763 |
LAH4 TFA |
LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 TFA possesses high plasmid DNA delivery capacities. LAH4 TFA has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes. |
|
| DC45770 |
Omiganan |
Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne. |
|
| DC45795 |
DprE1-IN-4 |
DprE1-IN-4 is a potent and orally active noncovalent DprE1 inhibitor with an IC50 of 0.90 μg/mL. DprE1-IN-4 exhibits potent in vitro activity against M. tuberculosis H37Rv and drug-resistant tuberculosis strain with MIC values of 0.12 μg/mL and 0.24 μg/mL, respectively. DprE1-IN-4 displays acceptable pharmacokinetic property and shows significant bactericidal activity in an acute mouse model of tuberculosis. |
|
| DC45865 |
Antofloxacin |
Antofloxacin is a well tolerate, orally active and broad-spectrum 8-amino-fluoroquinolone with potent antibacterial activities. Antofloxacin shows superior antibacterial activity against gyrA mutation-positive H. pylori strains, especially in Asn87- mutated strains, compared to levofloxacin. Antofloxacin is a weak, reversible inhibitor of CYP1A2 for the treatment of infections caused by a diverse group of bacterial species. |
|
| DC45875 |
Neamine tetrahydrochloride |
Neamine tetrahydrochloride, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine tetrahydrochloride is an anti-angiogenesis agent targeting angiogenin. Neamine tetrahydrochloride has potent antibacterial, antitumor and neuroprotective activities. |
|
| DC45890 |
T-91825 |
T-91825 (PPI-0903M), an N-phosphono-type cephalosporin, is the active form of TAK-599. T-91825 is active against both gram-positive and gram-negative bacteria. |
|
| DC45916 |
Ga(III) protoporphyrin IX |
Ga(III)protoporphyrin-IX is a model for the key interporphyrin interactions in malaria pigment. Ga(III)protoporphyrin-IX acts as a potent antibacterial against gram-negative, gram-positive, and acid-fast bacteria. Ga(III)protoporphyrin-IX is readily soluble in methanol (MeOH). Ga(III)protoporphyrin IX are as malarial pigment analogues for drug development and as potential antibacterial agents. |
|
| DC45926 |
(±)9-HpODE |
(±)9-HpODE is a long chain lipid hydroperoxide, is a product of linoleic acid peroxidation. (±)9-HpODE can induce oxidation of intracellular glutathione (GSH). (±)9-HpODE also exhibits antimicrobial activity against various fungal and bacterial pathogens. |
|
| DC45943 |
Fumagillol |
Fumagillol is a direct precursor of fumagillin. Fumagillin, as an antimicrobial agent, is a potent and selective inhibitor of angiogenesis. |
|
| DC45960 |
Matairesinoside |
Matairesinoside is a lignan with antibacterial and antioxidant activities. Matairesinoside also shows virus-cell fusion inhibitory activity. |
|
| DC45989 |
S-6123 |
S-6123 is a potent antimicrobial compound of the oxazolidinone series. S-6123 inhibits ribosomal protein synthesis without inhibiting DNA or RNA synthesis. |
|
| DC45998 |
Cassiaside B |
Cassiaside B, a naphthopyrone, has potent antimicrobial activity. |
|
| DC46010 |
Sanguisorbigenin |
Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA). |
|
| DC46015 |
Pangelin |
Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities. |
|
| DC46021 |
Benurestat |
Benurestat is an orally active urease inhibitor. Benurestat can be used for infected ureolysis research. |
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