Cat. No. | Product name | CAS No. |
DC4112 |
CP466722
Featured
CP-466722 is an potent and reversible ATM inhibitor. |
1080622-86-1 |
DC9306 |
CVT-313(NG-26)
Featured
CVT-313(NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor of CDK2 (IC50 = 0.5 uM for Cdk2/A and Cdk2/E; 4.2 uM for Cdk1/B; 215 uM for Cdk4/D1). |
199986-75-9 |
DC7810 |
CX-5461
Featured
CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA, has no effect on Pol II, and possesses 250-to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation. |
1138549-36-6 |
DC10775 |
Fadraciclib (CYC065)
Featured
CYC065 is an orally bioavailable inhibitor of cyclin dependent kinases 2, 5 and 9 (CDK2/5/9) with potential antineoplastic and chemoprotective activities. |
1070790-89-4 |
DC7325 |
CYC116
Featured
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM. |
693228-63-6 |
DC11446 |
Cycloastragenol
Featured
Cycloastragenol, the aglycone derivative of astragaloside A, can be found in various species of Astragalus and is reported to activate telomerase. |
84605-18-5 |
DC9013 |
Cyclophosphamide
Featured
Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. |
50-18-0 |
DCAPI1566 |
Cytarabine hydrochloride
Cytosine β-D-arabinofuranoside hydrochloride is an anti-leukemic agent which binds to topoisomerase I resulting in DNA fragmentation and inhibition of replication. In addition this compound does not have any effects on RNA synthesis. Cytosine β-D-arabinof |
69-74-9 |
DC11199 |
CZh226
Featured
CZh226 hydrochloride (CZh-226) is a potent, selective inhibitor of p21-activated kinase 4 (PAK4) with Ki of 9 nM, displays 346-fold selectivity over PAK-1. |
2196199-00-3 |
DC11198 |
CZh226 hydrochloride
CZh226 hydrochloride (CZh-226) is a potent, selective inhibitor of p21-activated kinase 4 (PAK4) with Ki of 9 nM, displays 346-fold selectivity over PAK-1. |
2231440-94-9 |
DC4197 |
Actinomycin D
Featured
Dactinomycin (also known generically as Actinomycin D ) is the most significant member of actinomycines, which are a class of polypeptide antibiotics isolated from soil bacteria of the genus Streptomyces. |
50-76-0 |
DC4125 |
PHA-739358 (danusertib)
Featured
Danusertib (PHA-739358) is an Aurora inhibitor for Aurora A/B/C, Bcr-Abl, c-RET and FGFR with IC50 of 13 nM/79 nM/61 nM, 25 nM, 31 nM and 47 nM, respectively. |
827318-97-8 |
DC7114 |
Dinaciclib (SCH727965)
Featured
Dinaciclib (SCH727965) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively. |
779353-01-4 |
DC4188 |
Doxorubicin hydrochloride
Featured
Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. |
25316-40-9 |
DC9983 |
E-7449
Featured
E7449 is an orally bioavailable, potent, small molecule inhibitor of PARP1 and PARP2; enhances the efficacy of radiotherapy and chemotherapy and has potent single agent anticancer activity in BRCA-deficient tumors. |
1140964-99-3 |
DC11192 |
Elacytarabine
Elacytarabine (CP-4055, CP4055) is a fatty acid derivative of cytarabine with potential antineoplastic activity. |
188181-42-2 |
DC10410 |
Ellipticine hydrochloride
Featured
Ellipticine hydrochloride is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. |
5081-48-1 |
DC8325 |
Ellipticine
Featured
Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor. |
519-23-3 |
DC7118 |
ENMD-2076
Featured
ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. |
934353-76-1 |
DC2102 |
Etoposide 4'-Phosphate
Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity. |
117091-64-2 |
DC11864 |
Fascaplysin (chloride)|CDK4 inhibitor
Featured
Fascaplysin is a potent, selective ATP-competitive CDK4 inhibitor (IC50 = 350 nM). |
114719-57-2 |
DC7413 |
Fasudil-HA
Featured
Fasudil Hcl(HA-1077; AT-877) is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, respectively. |
105628-07-7 |