| DC71391 |
L-Methionine-34S |
L-Methionine-34S is a 34S-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. |
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| DC71392 |
Fmoc-L-Lys (Boc)-OH-15N2 |
Fmoc-L-Lys (Boc)-OH-15N2 is a 15N-labeled Xanthine. Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation[1][2][3]. |
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| DC71393 |
Cortisol sulfate sodium |
Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol. Cortisol sulfate sodium is a specific ligand for intracellular transcortin.
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| DC71394 |
Leu-Leu-OH |
Leu-Leu-OH is a human endogenous metabolite. |
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| DC71395 |
Octacosanoic acid |
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models. |
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| DC71396 |
Guanidine thiocyanate |
Guanidine thiocyanate is a chaotropic agent. Guanidine thiocyanate can be used as a protein denaturant and a nucleic acid protector in the extraction of DNA and RNA from cells. |
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| DC71548 |
Glutathione oxidized disodium |
Glutathione oxidized disodium is produced by the oxidation of glutathione which is a major intracellular antioxidant and detoxifying agent. |
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| DC71549 |
PGE-M |
PGE-M is a metabolite of prostaglandin E2 (PEG2) as a biomarker of inflammation and cancer including advanced colorectal neoplasia, ovarian cancer, prostate cancer and so on. Urinary PGE-M is positively associated with obesity, smoking and lung metastases with breast cancer. |
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| DC71550 |
Adenosine 3',5'-diphosphate disodium |
Adenosine 3',5'-diphosphate disodium is an hydroxysteroid sulfotransferases inhibitor. |
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| DC71551 |
Adenylosuccinic acid tetraammonium |
Adenylosuccinic acid tetraammonium (Adenylosuccinate; Aspartyl adenylate) is a purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid tetraammonium can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid tetraammonium has the potential for the study of duchenne muscular dystrophy(DMD). |
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| DC71552 |
N-Lactoyl-Phenylalanine |
N-Lactoyl-Phenylalanine is a blood-borne signalling metabolite and can be used for obesity research. N-Lactoyl-Phenylalanine is exercise-inducible. |
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| DC71553 |
Inosine oxime |
Inosine oxime (6-Hydroxyadenosine) is an endogenous metabolite in the course of cell metabolism by cytochrome P450, by oxidative stress or by deviating nucleotide biosynthesis. Inosine oxime has toxic and mutagenic for procaryotic and eucaryotic cells. |
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| DC71554 |
BW B70C |
BW B70C is a potent, selective and orally activearachidonic acid 5-lipoxygenase inhibitor. BW B70C inhibits both acute and allergic bronchoconstriction and late-phase eosinophil accumulation subsequent to allergen inhalation in guinea-pigs. BW B70C prevents leukotriene C4 synthesis and reduces leucocyte migration to the airways lumen as well as albumin microvascular leakage. BW B70C has the potential for the research of anti-asthma drug. |
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| DC71555 |
Geranyl diphosphate |
Geranyl diphosphate is a key intermediate in the isoprenoid biosynthesis pathway (IBP).
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| DC71818 |
Folinic acid disodium |
Folinic acid (Leucovorin) disodium is a biological folic acid and is a forms of vitamin B9. Folinic acid disodium is generally administered along with Methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity. Folinic acid disodium and Sfluorouracil adjuvant chemotherapy shows effective in colon carcinoma. |
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| DC71819 |
Guanosine 5'-diphosphate sodium |
Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI). |
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| DC71820 |
Parathyroid hormone |
Parathyroid hormone (PTH) is a circulating hormone comprised of 84 amino acids. Parathyroid hormone is produced in the parathyroid glands and acts primarily on bone and kidney to maintain extracellular calcium levels within normal limits. Parathyroid hormone can be used for osteoporosis research. |
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| DC71821 |
S-Adenosyl-L-methionine (p-toluenesulfonate) |
S-Adenosyl-L-methionine (p-toluenesulfonate) is a naturally occurring molecule distributed to virtually all body tissues and fluids. S-Adenosyl-L-methionine takes parts in biochemical reactions involving enzymatic transmethylation, acting as a methyl group donor. S-Adenosyl-L-methionine can prevent mortality induced by Acetaminophen and acute and chronic lead poisoning in animals model. S-Adenosyl-L-methionine also possess antidepressant property. |
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| DC72058 |
Levoleucovorin |
Levoleucovorin (Levofolinic acid) is the pharmacologically active levoisomer of racemic leucovorin. Levoleucovorin can be used as a rescue agent after high-dose Methotrexate therapy, and in combination with fluorouracil for the research of advanced metastatic colorectal cancer.
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| DC72059 |
N-Acetyllactosamine |
N-Acetyllactosamine (LacNAc), a nitrogen-containing disaccharide, is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects. |
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| DC72060 |
D-Glyceraldehyde 3-phosphate |
D-Glyceraldehyde 3-phosphate (Triose phosphate) is a common molecule in living organisms and is an important intermediate in glycolysis and gluconeogenesis, as well as a sugar product of the Calvin cycle. D-Glyceraldehyde 3-phosphate is involved in the biosynthesis of tryptophan and thiamin. |
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| DC72226 |
2-Ethyl-2-hydroxybutanoic acid |
2-Ethyl-2-hydroxybutanoic acid (2-Ethyl-2-hydroxybutyric acid) is a hydroxy fatty acid. 2-Ethyl-2-hydroxybutanoic is a metabolite of DEHP. |
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| DC72227 |
Allolithocholic acid |
Allolithocholic acid is a steroid acid could found in normal serum and feces. Allolithocholic acid facilitates excretion, absorption, and transport of fats and sterols in the intestine and liver. |
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| DC72228 |
Glutathione oxidized-13C4,15N2 |
Glutathione oxidized (GSSG)-13C4,15N2 is the 13C and 15N labeled Glutathione oxidized. Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes. |
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| DC72229 |
ATP-13C10,15N5 disodium |
ATP-13C10,15N5 (Adenosine 5'-triphosphate-13C10,15N5) disodium is a 13C-labeled and 15N-labeled ATP. ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. |
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| DC72384 |
Ulodesine |
Ulodesine is a purine nucleoside phosphorylase (PNP) inhibitor. Ulodesine inhibits PNP with IC50 value of 2.293 nM/L. Ulodesine can be used for the research of hyporucicemia. |
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| DC72385 |
4-Hydroxyphenyl acetate |
4-Hydroxyphenyl acetate (4-HPA) is a natural antioxidant and protects cells from oxidative stress-induced necrosis. 4-Hydroxyphenyl acetate blocks the increase of cellular ROS induced by oxidative stress, and up-regulates NQO1 and HO-1 genes by stabilizing and inducing the nuclear translocation of NRF2 transcription factor. |
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| DC72386 |
MAHMA NONOate |
MAHMA NONOate is a NO donor. MAHMA NONOate effectively inhibits platelet aggregation induced by either collagen or ADP. |
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| DC72387 |
PAPA NONOate |
PAPA NONOate is a NO donor with a NO release half-life of 77 min (22-25°C). PAPA NONOate may represent a potential treatment for impaired wound healing in diabetes by increasing the rate of collagen synthesis at the wound site. |
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| DC72388 |
Virodhamine |
Virodhamine is an endocannabinoid, it regulates neurotransmission by activating the cannabinoid (CB) receptors. Virodhamine is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine induces megakaryocytic differentiation by triggering MAPK signaling and ROS production. Virodhamine can be used for the research of various neurological disorders such as Alzheimer's and Parkinson's diseases. |
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