| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC10656 | (+)-JQ1 carboxylic acid Featured | (+)-JQ1 carboxylic acid is the carboxylic acid form of (+)-JQ1 for derivative synthesis. |
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| DC5019 | (+)-JQ1 Featured | (+)-JQ1 is a BET bromodomain inhibitor, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. |
-JQ-1.gif)
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| DC12021 | (+)-JQ1 PA Featured | (+)-JQ1 PA is a Click-activated (alkyne) version of the BET bromodomain inhibitor (+)-JQ1. |
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| DCR-004 | Ellagic acid | >98%,Standard References |
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| DC10666 | MDK-7933 Featured | MDK-7933, also known as HDAC8-IN-1, is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). MDK-7933 was first reported in ChemMedChem. 2012 Oct;7(10):1815-24. MDK-7933 has CAS#1417997-93-3. |
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| DC5190 | 3-Deazaneplanocin A (DZNep） Featured | 3-deazaneplanocin A (DZNeP), an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM. |
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| DC10616 | 3-TYP Featured | 3-TYP is a selective SIRT3 inhibitor. |
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| DC8423 | 4SC-202 free base | 4SC-202 is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1. |
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| DC7592 | 4SC-202 Featured | 4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity. HDAC inhibitor 4SC-202 selectively binds to and inhibits class I HDACs leading to an acc |
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| DC11652 | Ischemin sodium | A cell permeable CBP bromodomain inhibitor with Kd of 19 uM. |
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| DC11653 | Ischemin | A cell permeable CBP bromodomain inhibitor with Kd of 19 uM. |
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| DC11813 | CM-414 | A first-in-class, dual inhibitor of PDE5 and HDAC that inhibits HDAC1/2/3/6 (IC50=310/490/322/91 nM, respectively) and PDE5 (IC50=60 nM). |
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| DC11815 | trans CM-414 | A first-in-class, dual inhibitor of PDE5 and HDAC that inhibits HDAC1/2/3/6 (IC50=310/490/322/91 nM, respectively) and PDE5 (IC50=60 nM). |
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| DC11814 | cis CM-414 | A first-in-class, dual inhibitor of PDE5 and HDAC that inhibits HDAC1/2/3/6 (IC50=310/490/322/91 nM, respectively) and PDE5 (IC50=60 nM). |
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| DC7565 | BET bromodomain inhibitor,cas 1505453-59-7 | A new compound which is similar with +JQ-1，BET bromodomain inhibitor |
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| DC11793 | UMB-32 | A novel a potent, selective inhibitor of BRD4 with Kd of 550 nM, cellular IC50 of 724 nM. |
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| DC11792 | UMB-136 | A novel bromodomain BRD4 inhibitor that significantly induces HIV-1 reactivation. |
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| DC11880 | TH1834 | A novel potent specific histone acetyltransferaseTip60 inhibitor. |
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| DC11881 | TH1834 dihydrochloride | A novel potent specific histone acetyltransferaseTip60 inhibitor. |
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| DC11696 | CM-579 | A novel potent, selective and reversible dual inhibitor of G9a/DNMTs with IC50 of 16 nM and 32 nM for G9a and DNMT1, respectively. |
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| DC11585 | MZ-242 | A novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM. |
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| DC11587 | SirReal1 Featured | A novel potent, selective Sirt2 inhibitor with IC50 of 3.745 uM. |
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| DC11730 | GNE-207 | A novel potent, selective, orally active CBP/p300 bromodomain with IC50 of 1.0 nM. |
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| DC11917 | (R)-OR-S1 | A novel SAM-competitive, highly selective, orally bioavailable EZH1/2 dual inhibitor with IC50 of 16/50 nM, respectively. |
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| DC11596 | SB-379278A | A potent and selective HDAC8 inhibitor with IC50 of 0.5 uM.. |
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| DC11595 | NCC-149 | A potent and selective HDAC8 inhibitor with IC50 of 70 nM. |
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| DC11568 | HJB-97 | A potent BET bromodomian inhibitor with IC50 of 3-7 nM for BRD2/3/4 BD1 and BD2.. |
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| DC11820 | A-893 | A potent, selective and cell active lysine methyltransferase SMYD2 inhibitor with IC50 of 2.8 nM. |
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| DC11511 | A-485 Featured | A potent, selective and, cell and in vivo active p300/CBP catalytic inhibitor with IC50 of 9.8/2.6 nM. |
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| DC11597 | SB-429201 | A potent, selective HDAC1 inhibitor with IC50 of 1.5 uM. |
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