DC66000 |
N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea
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N-[(1R)-4-[(Aminoiminomethyl)amino]-1-[[[(1R)-1-(4-hydroxyphenyl)ethyl]amino]carbonyl]butyl]-α-phenylbenzeneacetamide is an anticonvulsant agent with potential for the treatment of generalized tonic-clonic and partial seizures. |
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DC66001 |
(E)-2-((5-nitrofuran-2-yl)methylene)hydrazine-1-carboxamide
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DC66002 |
Retinoic acid, methyl ester
Featured
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DC66003 |
4-Keto all-trans-Retinoic Acid Methyl Ester
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DC66004 |
NS3861
Featured
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NS3861 is an agonist of nicotinic acetylcholine receptors (nAChRs) and binds with high affinity to heteromeric α3β4 nAChR. The binding Ki values of 0.62, 25, 7.8, 55 nM for α3β4, α3β2, α4β4, α4β2, respectively. |
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DC66005 |
2-(indolin-1-yl)-1-(4-(naphthalen-2-ylsulfonyl)piperazin-1-yl)ethan-1-one
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DC66006 |
Protein kinase inhibitor 6
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Protein kinase inhibitor 6 is a protein kinase inhibitor. |
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DC66007 |
CDK9-IN-15
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CDK9-IN-15 (compound 50) is a potent CDK9 inhibitor. |
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DC66008 |
PARP-1-IN-2
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PARP-1-IN-2 (compound 11g) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 149 nM. PARP1-IN-2 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549. PARP1-IN-2 can induce A549 cells apoptosis. |
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DC66009 |
M4 mAChR agonist-1
Featured
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M4 mAChR agonist-1 (compound 10a) is a potent M4 mAChR agonist with an EC50 >10 μM for human M4. |
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DC66010 |
HIF1-IN-3
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HIF1-IN-3 (compound F4) is a potent HIF1 inhibitor with an EC50 value of 0.9 μM. HIF1-IN-3 can be used for researching anticancer. |
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DC66011 |
PARP1-IN-8
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PARP1-IN-8 (compound 11c) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 97 nM. PARP1-IN-8 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549. |
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DC66012 |
JAMM protein inhibitor 2
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JAMM protein inhibitor 2 (compound 180) is a potent JAMM protease inhibitor with IC50s of 10 μM, 46 μM and 89 μM for thrombin, Rpn11 and MMP2, respectively. JAMM protein inhibitor 2 can be used for researching anticancer |
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DC66013 |
(2-(1H-benzo[d][1,2,3]triazol-1-yl)acetyl)alanine
Featured
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DC66014 |
(2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid
Featured
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DC66015 |
3-methyl-N-(3-(thiazolo[5,4-b]pyridin-2-yl)phenyl)butanamide
Featured
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DC66016 |
Benzo[d]thiazol-2-ylmethyl ((2-fluorophenyl)sulfonyl)-L-alaninate
Featured
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DC66017 |
WAY324208
Featured
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DC66018 |
Sirtuin modulator 7
Featured
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Sirtuin modulator 7 is a sirtuin-modulating compound which may increase the lifespan of a cell, and may be used for research of diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and flushing which would benefit from increased mitochondrial activity. |
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DC66019 |
WAY327059
Featured
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DC66020 |
4-(((3-(4-Ethoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)methyl)benzonitrile
Featured
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DC66021 |
WAY-328122
Featured
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DC66022 |
WAY-324485
Featured
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DC66023 |
WAY-642481
Featured
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DC66024 |
2-(4-Chlorophenyl)-N-(4-(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)phenyl)acetamide
Featured
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DC66025 |
WAY-324284-A
Featured
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DC66026 |
HIV-IN-6
Featured
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HIV-IN-6 is a HIV-Ⅰ viral replication inhibitor by targeting Src family kinases (SFK) that interact with Nef protein of the virus, such as Hck. |
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DC66027 |
CFTR corrector 9
Featured
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CFTR corrector 9 (compound 42) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator. CFTR corrector 9 can be used for researching cystic fibrosis (CF) and other CFTR associated disorders. |
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DC66028 |
WAY-313170
Featured
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inhibition of hedgehog signaling and phosphodiesterase; inhibition of hedgehog signaling and phosphodiesterase. |
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DC66029 |
WAY-639234
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