Cat. No. | Product name | CAS No. |
DC71742 |
MY-875
Featured
MY-875 is a competitive microtubulin polymerization inhibitor with an IC50 value of 0.92 μM. MY-875 inhibits microtubulin polymerization by targeting colchicine binding sites and activates the Hippo pathway. MY-875 induces apoptosis and has anticancer activity. |
|
DC71744 |
MIND4-19
Featured
MIND4-19 is a potent SIRT2 inhibitor with an IC50 value of 7.0 μM. MIND4-19 can be used for researching Huntington's disease. |
129544-85-0 |
DC71745 |
Sirtuin modulator 2
Featured
Sirtuin modulator 2 (Compound 132) is a sirtuin modulator with an ED50 equal or less than 50 μM. |
667910-69-2 |
DC71747 |
Aripiprazole monohydrate
Featured
Aripiprazole (OPC-14597) monohydrate, an atypical antipsychotic, is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole monohydrate is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A, 5-HT2C, D3, and D4 receptors. Aripiprazole monohydrate can be used for the research of schizophrenia and COVID19. |
851220-85-4 |
DC71752 |
2'-MeCCPA
Featured
2'-MeCCPA is a potent and selective A1 adenosine receptors (A1AR) agonist. 2'-MeCCPA efficiently inhibits cAMP modulation in both direct pathway medium spiny neurons (dMSNs) and indirect pathway medium spiny neurons (iMSNs). |
205171-12-6 |
DC71814 |
SPH3127
Featured
SPH3127 (DRI 18) is a novel, highly potent, and orally active direct renin inhibitor (recombinant human-renin IC50=0.4 nM, human plasma renin activity IC50=0.45 nM). SPH3127 shows antihypertensive effect and can be used in essential hypertension research. |
1399849-02-5 |
DC71825 |
Chitosan oligosaccharide
Featured
Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. Chitosan oligosaccharide (COS) activates AMPK and inhibits inflammatory signaling pathways including NF-κB and MAPK pathways. |
148411-57-8 |
DC71826 |
Enclomiphene hydrochloride
Featured
Enclomiphene ((E)-Clomiphene) dihydrochloride is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene dihydrochloride can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes. |
14158-65-7 |
DC71835 |
(R)-RP-6306
Featured
(R)-RP-6306 (183) can be used for the research of Myt1 mediated diseases and kinds of cancer for slowing the progression of cancer. |
2719793-91-4 |
DC71836 |
DOPA-NA
Featured
DOPA-NA is an anionic lipid that can be used to prepare liposomes, micelles and artificial membranes. |
108392-02-5 |
DC71843 |
BAY 1135626
Featured
BAY 1135626 is used to synthesize BAY 1129980, and use to anti-tumor research. BAY 1129980 is a Auristatin-based anti-C4.4A (LYPD3) antibody–drug conjugate (ADC), is used to non–small cell lung cancer (NSCLC) research. |
1404071-37-9 |
DC71847 |
C24-Ceramide
Featured
C24-Ceramide is a sphingolipid that can be used for the lipid membranes composed. C24-Ceramide induces time-dependent changes in membrane properties. C24-Ceramide induces membrane reorganization. |
102917-80-6 |
DC71874 |
MIF098
Featured
MIF098 is a macrophage migration inhibitory factor (MIF) antagonist. MIF098 inhibits proliferation, migration and fibrosis of pulmonary smooth muscle cells. MIF098 can be used for immunoinflammation-related disease research. |
1208448-95-6 |
DC71882 |
Palvanil
Featured
Palvanil is a capsaicin analogue, shows strong desensitizing capability against the TRPV1 receptor. Palvanil shows anti-nociceptive and anti-inflammation effects. |
69693-13-6 |
DC71892 |
TAS1553
Featured
TAS1553 is a potent, orally active protein–protein interaction (PPI) inhibitor with an IC50 values of 0.0396 μM. TAS1553 inhibits DNA replication and reduces intracellular dATP pool. TAS1553 induces apoptosis. TAS1553 can be used for cancer research. |
2166023-31-8 |
DC71898 |
GLN-1062
Featured
GLN-1062 (Memogain) is an inactive pro-drug of galantamine, the latter being a plant alkaloid approved for the treatment of mild to moderate Alzheimer's disease. |
224169-27-1 |
DC71900 |
MM3122
Featured
MM-3122 is a selective inhibitor of host cell serine protease TMPRSS2 (transmembrane protease serine 2) with IC50 of 0.34 nM against recombinant full-length TMPRSS2 protein. |
2574390-27-3 |
DC71902 |
WAY-296817
Featured
WAY-296817 is casein kinase 1 (CK1) inhibitor and can be used for research on the treatment or prevention. |
349438-74-0 |
DC71909 |
Exarafenib
Featured
Exarafenib (RAF/KIN_2787) is a potent, orally active pan-RAF inhibitor. Exarafenib has anticancer activity by suppression of downstream MAPK pathway signaling. Exarafenib can be used for cancer research. |
2639957-39-2 |
DC71910 |
Tinlorafenib
Featured
Tinlorafenib (PF-07284890) (compound 10) is an orally active BRAF kinase inhibitor, with IC50s of 4.25 and 2.7 nM for BRAFV600E/V600K respectively. Tinlorafenib demonstrates CNS penetration and can be used in the research of BRAF-associated malignant and benign tumors of the CNS as well as extracranial malignancies[1]. |
2573781-75-4 |
DC71953 |
dTAGV-1-NEG
Featured
dTAGV-1-NEG is a diastereomer and as a heterobifunctional negative control of dTAGV-1. dTAGV-1 is an FKBP12F36V-selective degrader. |
2451573-87-6 |
DC71956 |
BMS-986339
Featured
BMS-986339 is an orally active, potent FXR agonist. BMS-986339 forms H-bond with His298 and ASN287 residues. |
2477873-64-4 |