Cat. No. | Product name | CAS No. |
DC8642 |
Lorediplon
Featured
Lorediplon is a new GABAA modulator Drug for treatment of insomnia. |
917393-39-6 |
DCAPI1574 |
Nefiracetam
Nefiracetam is a nootropic of the racetam family. Nefiracetam is cognitive enhancer with an IC50 of approximately 150–200 μM for Ro 5-4864. This compound activates L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems. Nefiracetam di |
77191-36-7 |
DC8083 |
NS11394
Featured
NS11394 possesses a functional efficacy selectivity profile of alpha(5) > alpha(3) > alpha(2) > alpha(1) at GABA(A) alpha subunit-containing receptors. |
951650-22-9 |
DC11267 |
ONO-8590580
Featured
ONO-8590580 is a Novel GABAAα5 Negative Allosteric Modulator Enhances Long-Term Potentiation and Improves Cognitive Deficits in Preclinical Models. |
1802661-73-9 |
DC10292 |
Pagoclone
Pagoclone is an active (+)-enantiomer of the racemate RP 59037. Pagoclone is a partial GABA(A) receptor agonist used for the treatment of panic and anxiety disorders. |
133737-32-3 |
DC10113 |
Pipequaline
Featured
Pipequaline (PK 8165) is a partial benzodiazepine receptor agonist with anxiolytic activity. |
77472-98-1 |
DCAPI1330 |
Piracetam
Piracetam is a cyclic derivative of the neurotransmitter ã-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders. |
7491-74-9 |
DC10578 |
rac BHFF
Featured
Rac BHFF is a potent and selective GABAB receptor positive allosteric modulator that increases the efficacy and potency of GABA ( > 149% and > 15-fold respectively). Orally active and exhibits anxiolytic activity in vivo. |
123557-91-5 |
DC8099 |
Saclofen
Featured
Saclofen is a selective GABAB antagonist. |
125464-42-8 |
DC10651 |
SSD114 hydrochloride
Featured
SSD114 is a novel GABAB positive allosteric modulator. |
2319790-02-6 |
DC8896 |
Tiagabine hydrochloride
Featured
Tiagabine(NO328) is a selective gamma-aminobutyric acid (GABA) reuptake inhibitor. |
145821-59-6 |
DC11319 |
TPMPA
Featured
TPMPA is a GABAA-ρ1 (ρ1 GABAC) receptor antagonist that is 8-fold selective for GABAA-ρ1 over GABAA-ρ2 (ρ2 GABAC) receptors expressed in X. |
182485-36-5 |
DC9958 |
U 93631
Featured
U93631 is a GABAA receptor ligand of novel chemical structure with IC50 of 100 nM,and has been shown to induce a rapid, time-dependent decay of GABA-induced whole-cell Cl-currents in recombinant GABAA receptors. |
152273-12-6 |
DC9560 |
Vigabatrin (Hydrochloride)
Vigabatrin Hcl(γ-Vinyl-GABA; Sabril) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase. |
1391054-02-6 |
DC9541 |
Vigabatrin
Featured
Vigabatrin(γ-Vinyl-GABA; Sabril) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase. IC50 value: Target: GABA transaminase Clinical studies have sh |
68506-86-5 |
DC7642 |
Α5ia (α5IA)
α5IA is a selective inverse agonist for Α5 subtype of GABAA receptor with a higher intrinsic activity at the A5 subtype than other drugs. |
215874-86-5 |
DC11117 | KRM-II-81 | 2014348-91-3 |
DC28110 |
FG 7142
Featured
FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the |
78538-74-6 |
DC28164 |
Ro15-4513
Featured
Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR). Ro15-4513 is a potent ethanol antagonist. Ro15-4513 has anti-anxiety effect. |
91917-65-6 |
DC28546 |
Clomethiazole
Chlormethiazole is an potent and orally active GABAA agonist. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Chlormethiazole is an anticonvulsant agent and has the potential for treating convulsive status epilepticus. |
533-45-9 |
DC28579 |
(E)-GABAB receptor antagonist 1
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. GABAB receptor antagonist 1 (compound 14) is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. |
1611483-29-4 |
DC40080 |
(2S)-6-Prenylnaringenin
(2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface. |
68236-13-5 |