DCC3024 |
Lassbio-1366 |
Novel Adenosine A2a Receptor Agonist, Attenuating the Progression of Monocrotaline-induced Pulmonary Hypertension |
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DCC3025 |
Lassbio-1524 |
Novel IKK-β inhibitor, reducing the secretion of TNF-α, IL-1β, IL-6, IL-12, IFN-γ and increased secretion of IL-10, protecting gastrointestinal homeostasis |
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DCC3026 |
Lassbio-1829 Hydrochloride |
Novel orally active IKK2 inhibitor |
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DCC3027 |
Lassbio-1911 |
Novel Potent and Selective Histone Deacetylase 6 (HDAC6) Inhibitor |
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DCC3028 |
Latonduine A |
Natural F508del-CFTR corrector, inhibiting both PARP-3 and -16, regulating the activity of the unfolded protein response activator inositol-requiring enzyme (IRE-1) via modulation of the level of its ribosylation by PARP-16 |
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DCC3029 |
Latonduine B |
Natural F508del-CFTR trafficking corrector, targeting poly(ADP-ribose) polymerase (PARP) |
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DCC3030 |
Latrunculin A |
Disruptor of microfilament-mediated processes |
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DCC3031 |
Laulimalide |
Microtubule stabilzer, potently inhibiting cellular proliferation in cancer cell lines |
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DCC3032 |
Laxaphycin A |
Natural antifungal and cytotoxic agent |
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DCC3033 |
Laxaphycin B |
Natural inhibitor of the proliferation of sensitive and resistant human cancer cell lines and this inhibitory activity is strongly increased in the presence of laxaphycin A |
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DCC3034 |
Lb30870 |
Potent, orally active, selective and direct thrombin inhibitor |
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DCC3035 |
Lb30889 |
Prodrug of LB30870 as potent, orally active, selective and direct thrombin inhibitor |
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DCC3036 |
L-bmaa Hydrochloride |
Neurotoxic amino acid |
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DCC3037 |
Lc0024 |
Novel antibiofilm coating, covalently bindng to a titanium implant surface (LC0024-Ti) |
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DCC3038 |
Lcat Activator A |
Novel activator of Lecithin:cholesterol acyltransferase (LCAT) including some familial mutations, by forming a hydrophobic adduct with Cys31 |
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DCC3039 |
Lcb03-0110 |
Novel potent angiogenesis inhibitor, inhibiting VEGFR-2 and JAK/STAT3 signalling in primary cultured human endothelial cells and cancer cells |
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DCC3040 |
Lcl-peg3-n3 |
Novel clickable linker for estrogen receptor degraders |
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DCC3041 |
Lcrf-0004 |
Novel potent and selective RON receptor tyrosine kinase inhibitor |
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DCC3042 |
Ldc0496 |
Novel potent and selective covalent inhibitor of EGFR and Her2 exon20 insertion mutations, exhibiting selectivity over wild type EGFR and within the kinome |
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DCC3043 |
Ldc7559 |
Novel potent inhibitor of the NOX2-dependent oxidative burst in neutrophils by activating the glycolytic enzyme phosphofructokinase-1 liver type (PFKL) and dampening flux through the pentose phosphate pathway |
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DCC3044 |
Ldc8201 |
Novel potent and selective covalent inhibitor of EGFR and Her2 exon20 insertion mutations, exhibiting selectivity over wild type EGFR and within the kinome |
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DCC3045 |
Ldd-1819 |
Novel dual inhibitor of GSK-3β and aurora kinase A, increasing somatic cell plasticity and inhibiting tumorigenicity |
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DCC3046 |
Ldd970 |
Novel Aurora Kinase A Inhibitor |
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DCC3047 |
Lddn-0003499 |
Novel Src family tyrosine kinase inhibitor with anti-inflammatory effects in response to Aß stimulation of microglia |
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DCC3048 |
Ldha-in-22y |
Novel inhibitor of human lactate dehydrogenase A (LDHA) |
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DCC3049 |
Ldn-0028574 |
Novel Inhibitor of SIRT1; Inhibitor of the human MDM2-p53 interaction |
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DCC3050 |
Ldn-0044878 |
Novel PAK3 kinase inhibitor, inhibiting p53-inactivated cancers |
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DCC3051 |
Ldn-0070977 |
Novel inhibitor of PERK stress-dependent eIF2α phosphorylation with no toxicity to the cells |
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DCC3052 |
Ldn-0130436 |
Novel TDP-43::GFP aggregation inhibitor |
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DCC3053 |
ldn-112006 |
Necroptosis inhibitor |
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