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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC3024 Lassbio-1366 Novel Adenosine A2a Receptor Agonist, Attenuating the Progression of Monocrotaline-induced Pulmonary Hypertension
DCC3025 Lassbio-1524 Novel IKK-β inhibitor, reducing the secretion of TNF-α, IL-1β, IL-6, IL-12, IFN-γ and increased secretion of IL-10, protecting gastrointestinal homeostasis
DCC3026 Lassbio-1829 Hydrochloride Novel orally active IKK2 inhibitor
DCC3027 Lassbio-1911 Novel Potent and Selective Histone Deacetylase 6 (HDAC6) Inhibitor
DCC3028 Latonduine A Natural F508del-CFTR corrector, inhibiting both PARP-3 and -16, regulating the activity of the unfolded protein response activator inositol-requiring enzyme (IRE-1) via modulation of the level of its ribosylation by PARP-16
DCC3029 Latonduine B Natural F508del-CFTR trafficking corrector, targeting poly(ADP-ribose) polymerase (PARP)
DCC3030 Latrunculin A Disruptor of microfilament-mediated processes
DCC3031 Laulimalide Microtubule stabilzer, potently inhibiting cellular proliferation in cancer cell lines
DCC3032 Laxaphycin A Natural antifungal and cytotoxic agent
DCC3033 Laxaphycin B Natural inhibitor of the proliferation of sensitive and resistant human cancer cell lines and this inhibitory activity is strongly increased in the presence of laxaphycin A
DCC3034 Lb30870 Potent, orally active, selective and direct thrombin inhibitor
DCC3035 Lb30889 Prodrug of LB30870 as potent, orally active, selective and direct thrombin inhibitor
DCC3036 L-bmaa Hydrochloride Neurotoxic amino acid
DCC3037 Lc0024 Novel antibiofilm coating, covalently bindng to a titanium implant surface (LC0024-Ti)
DCC3038 Lcat Activator A Novel activator of Lecithin:cholesterol acyltransferase (LCAT) including some familial mutations, by forming a hydrophobic adduct with Cys31
DCC3039 Lcb03-0110 Novel potent angiogenesis inhibitor, inhibiting VEGFR-2 and JAK/STAT3 signalling in primary cultured human endothelial cells and cancer cells
DCC3040 Lcl-peg3-n3 Novel clickable linker for estrogen receptor degraders
DCC3041 Lcrf-0004 Novel potent and selective RON receptor tyrosine kinase inhibitor
DCC3042 Ldc0496 Novel potent and selective covalent inhibitor of EGFR and Her2 exon20 insertion mutations, exhibiting selectivity over wild type EGFR and within the kinome
DCC3043 Ldc7559 Novel potent inhibitor of the NOX2-dependent oxidative burst in neutrophils by activating the glycolytic enzyme phosphofructokinase-1 liver type (PFKL) and dampening flux through the pentose phosphate pathway
DCC3044 Ldc8201 Novel potent and selective covalent inhibitor of EGFR and Her2 exon20 insertion mutations, exhibiting selectivity over wild type EGFR and within the kinome
DCC3045 Ldd-1819 Novel dual inhibitor of GSK-3β and aurora kinase A, increasing somatic cell plasticity and inhibiting tumorigenicity
DCC3046 Ldd970 Novel Aurora Kinase A Inhibitor
DCC3047 Lddn-0003499 Novel Src family tyrosine kinase inhibitor with anti-inflammatory effects in response to Aß stimulation of microglia
DCC3048 Ldha-in-22y Novel inhibitor of human lactate dehydrogenase A (LDHA)
DCC3049 Ldn-0028574 Novel Inhibitor of SIRT1; Inhibitor of the human MDM2-p53 interaction
DCC3050 Ldn-0044878 Novel PAK3 kinase inhibitor, inhibiting p53-​inactivated cancers
DCC3051 Ldn-0070977 Novel inhibitor of PERK stress-dependent eIF2α phosphorylation with no toxicity to the cells
DCC3052 Ldn-0130436 Novel TDP-43::GFP aggregation inhibitor
DCC3053 ldn-112006 Necroptosis inhibitor

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