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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC3384 Mk-0493 Novel potent, orally active and selective agonist of the melanocortin receptor 4 (MC4R)
DCC3385 mk-0499 The class III antiarrhythmic agent, blocking HERG, a human cardiac delayed rectifier K+ channel
DCC3386 Mk-0626 Novel Dipeptidyl peptidase IV (DPP-4) inhibitor, improving neovascularization by increasing both the number of circulating endothelial progenitor cells and endothelial nitric oxide synthetase expression
DCC3387 Mk-0633 Tosylate Potent and Selective 5-Lipoxygenase Inhibitor
DCC3388 Mk-0736 Selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor
DCC3389 Mk-0916 Selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor
DCC3390 Mk-1220 Novel Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure
DCC3391 Mk-1597 Novel renin inhibitor
DCC3392 Mk-2295 Potent TRPV1 antagonist
DCC3393 Mk-386 Potent and selective human type-1 5alpha-reductase inhibitor
DCC3394 Mk-4541 Novel Selective Androgen Receptor Modulator (SARM)
DCC3395 Mk-5046 Novel nonpeptide bombesin receptor subtype-3 agonist
DCC3396 Mk-6884 Novel potent muscarinic acetylcholine receptor 4 (M4) positive allosteric modulator (PAM)
DCC3397 Mk-7725 Novel bombesin receptor subtype-3 (BRS-3) modulator
DCC3398 Mk-8245 Analog Novel liver-targeting inhibitor of stearoyl-CoA desaturase (SCD)
DCC3399 Mk-8666 Tromethamine Novel agonist of G-protein coupled receptor 40 (GPR40)
DCC3400 Mk-8970 Prodrug of raltegravir with enhanced colonic absorption
DCC3401 Mkk3/6-in-6 Novel potent and selective MKK3/6 inhibitor
DCC3402 Mkp5-in-1 Novel highly specific, potent, orally bioavailable MKP5 inhibitor
DCC3403 Km04794 Novel endoplasmic reticulum proteostasis modulator, enhancing insulin production in pancreatic β cells, inhibiting the UPR, alleviating ER stress and protein aggregation, improving intracellular insulin levels and insulin secretion
DCC3404 ml312 Novel Inhibitor of Scavenger Receptor BI-mediated Lipid Uptake
DCC3405 Mlck Inhibitor Peptide-18 Selective inhibitor of Myosin Light Chain Kinase (MLCK)
DCC3406 Mln-0415 Novel IKK2 inhibitor, decreasing NF-κB activation and down-regulating the expression of a number of inflammatory proteins
DCC3407 Mln944 Novel potent DNA binding agent, stabilizing topoisomerase-dependent cleavage, demonstrating exceptional efficacy against a number of murine and human tumor models
DCC3408 Mln-977 Second generation 5-LO inhibitor, blocking the production of leukotrienes
DCC3409 Mls000099089 Novel selective and potent inhibitor of recombinant h12/15-LOX and cellular mouse 12/15-LOX (m12/15-LOX)
DCC3410 Mls000536924 Potent and selective competitive inhibitor of human epithelial 15-lipoxygenase-2 (15-LOX-2)
DCC3411 Mls000545091 Potent and selective mixed-type inhibitor of human epithelial 15-lipoxygenase-2 (15-LOX-2)
DCC3412 Mls000733230 Novel potent inhibitor of EBOV infection
DCC3413 Mls001158554 Novel Inhibitor of Human Cytomegalovirus

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