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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC3689 Nomegestrol Acetate Neutral, nonandrogenic, progesterone-like profile progestin
DCC3690 Nonoxynol-9 Novel human epidermal growth factor receptor-2 (HER2) inhibitor; Spermatocide
DCC3691 Nord-1 Novel red-light-controllable nitric oxide (NO) releaser
DCC3692 Nor-fauc-365 FAUC-365 analog
DCC3693 Norgestomet Steroidal progestin used in veterinary medicine to control estrus and ovulation in cattle
DCC3694 Noricumazole A Secondary metabolite from the myxobacterium Sorangium cellulosum, acting as a potent HCV inhibitor, Ebola virus (EBOV) entry inhibitor, and a potassium channel inhibitor
DCC3695 No-rosa5 Controllable nitric oxide (NO) donor, releasing NO triggered by photoinduced electron transfer (PeT)
DCC3696 Noscapine Natueal sigma receptor agonist, attenuating cytokine release associated with SARS-CoV-2, also being used as anti-malarial, anti-stroke and cough-suppressant
DCC3697 Notum-in-23dd Novel potent inhibitor of notum carboxylesterase activity
DCC3698 Notum-in-24 Novel potent notum inhibitor (OPTS IC50 3.6nM; TCF-LEF EC50 220nM), showing good plasma exposure and reasonable CNS penetration
DCC3699 Nov-lrrk2-11 Novel potent LRRK2 inhibitor
DCC3700 Novolactone Natural inhibitor of the allosteric regulation of Hsp70
DCC3701 Np-005497 Natural inhibitor of jasmonate signaling targets JAR1 in Arabidopsis thaliana
DCC3702 Npa101.3 Second-Generation RET/VEGFR2 Inhibitor
DCC3703 Np-c86 Novel stabilizer of long noncoding RNA (lncRNA) GAS5, binding to GAS5 with high affinity, and increasing GAS5 levels and glucose uptake in diabetic patient adipocytes
DCC3704 Npd-008 Novel Inhibitor of Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1)
DCC3705 Npd-039 Novel Inhibitor of Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1)
DCC3706 Npd-048 Novel inhibitor of Trypanosoma brucei PDEB1 (TbrPDEB1)
DCC3707 Npd11033 Novel selective SIRT2 inhibitor, creating a hydrophobic cavity behind the substrate-binding pocket after a conformational change of the Zn-binding small domain of SIRT2
DCC3708 Npd12671 Novel activator of 15-ADON production, significantly increasing the transcription of Tri6, a transcription factor gene necessary for trichothecene biosynthesis, in both trichothecene-inducing and noninducing culture conditions
DCC3709 Npd2639 Novel biomediator, inducing reveromycin production in Streptomyces sp. SN-593
DCC3710 Npd6689 Novel tubulin inhibitor
DCC3711 Npd7155 Novel competitive MTH1 inhibitor
DCC3712 Npd8617 Novel tubulin inhibitor
DCC3713 Npd9055 Novel heterotrimeric G-protein Gi modulator, inhibiting GDP/GTP exchange on a Gαi subunit induced by a G-protein-coupled receptor agonist, but not on another G-protein from the Gαs family, regulating Gβγ-dependent cellular processes, most likely by causin
DCC3714 Nplc0393 Novel inhibitor of TGF-β1 signaling pathway, inhibiting the upregulation of MAT2A mechanistically, dose-dependently activating PP2Cα and efficiently alleviating liver fibrosis
DCC3715 Npr-c Activator 1 Novel potent activator of the natriuretic peptide receptor C (NPR-C) with EC 50 ~1 μM
DCC3716 Nps-89636 Calcilytic negative allosteric modulator of calcium-sensing receptor (CaR)
DCC3717 Nqo1 Substrate 1 Novel substrate for NAD(P)H: quinone oxidoreductase 1 (NQO1), acting as an effective intracellular ROS generator for the treatment of drug-resistant non-small-cell lung cancer
DCC3718 Nr2b-in-1 Novel NMDA/NR2B Antagonist

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