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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC3804 Nsc-8891 Tyrosyl-DNA phosphodiesterase (Tdp1) inhibitor
DCC3805 Nsc-9037 First-in-class probe of Rad6 function, inhibiting Rad6 function and Rad6-Rad18 interaction in the PCNA ubiquitination cascade
DCC3806 nsc-96626 Novel B-Raf(V600E) inhibitor
DCC3807 Nsi-189 Phosphate Novel stimulator of neurogenesis of human hippocampus-derived neural stem cells in vitro and in vivo.
DCC3808 Nsmase2-in-1 Novel inhibitor of neutral sphingomyelinase 2 (nSMase2) for the treatment of neurodegenerative diseases
DCC3809 Nsp-116 Novel free radical scavenger, against light-induced photoreceptor cell damage
DCC3810 Nti-007 Potent anti-HBV agent, targeting the NTCP-APOA1-HBx-Beclin1-mediated autophagic pathway
DCC3811 Ntrc-739 Novel nonpeptide selective ligand for NTS2
DCC3812 Ntrc-808 Novel nonpeptide potent and selective partial agonist of the Neurotensin receptor type 2 (NTS2)
DCC3813 Ntrd22 Novel Allosteric Modulator of RNA Binding Targeting the N-Terminal Domain of TDP-43
DCC3814 Ntr-responsive Protac 17-1 The first NTR-responsive PROTAC, incorporating the caging group on the Von Hippel-Lindau (VHL) E3 ubiquitin ligase ligand, efficiently degrading the EGFR protein and subsequently exert antitumor efficacy
DCC3815 Ntz-15 Novel potent STAT3 inhibitor, exhibiting much improved in vivo pharmacokinetic parameters in rats and efficacies against proliferations in multiple cancer cell lines
DCC3816 Ntz-24 Novel potent STAT3 inhibitor
DCC3817 Ntzdpa Novel potent and selective non-thiazolidinedione partial Peroxisome_proliferator-activated_receptor>PPARγ agonist, acting as an antibiotic effectively against bacterial persisters
DCC3818 Nu6155 Novel potent CDK2 inhibitor
DCC3819 Nuc013 Novel DNA methytransferase inhibitor, be significantly safer and more effective than decitabine in xenograft models of human leukemia and colon cancer
DCC3820 Nucc-201177 Novel highly potent and selective MEK4 inhibitor
DCC3821 Nucc-474 Novel potent activin antagonist
DCC3822 Nucc-555 First-in-class activin antagonist, specifically binding to ALK4, which opens a completely new approach to inhibiting the activity of TGF-beta receptor superfamily members
DCC3823 Nucleocidin Nucleosidic antibiotic
DCC3824 Nuod-in-25 Novel inhibitor of Helicobacter pylori , targeting H. pylori's respiratory complex I subunit NuoD
DCC3825 Nurf Inhibitor Bz1 Novel Potent Cell-Active Inhibitor of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition
DCC3826 Nusb-nuse Inhibitor-22 Novel Inhibitor of the NusB-NusE Protein-Protein Interaction with Antibiotic Activity
DCC3827 Nusb-nuse Interaction Inhibitor-1 Novel modulator of the NusB-NusE interaction
DCC3828 Nutlin-1 p53-MDM2 binding inhibitor; p-Glycoprotein (p-gp) transport substrate; Antitumer agent
DCC3829 Nutlin-2 Potent and selective p53-MDM2 binding inhibitor
DCC3830 Nv2899 Novel translational readthrough-inducing drug (TRID), rescuing the functional full-length protein expression in genetic diseases, such as cystic fibrosis, caused by premature termination codons (PTCs)
DCC3831 Nv2907 Novel translational readthrough-inducing drug (TRID), rescuing the functional full-length protein expression in genetic diseases, such as cystic fibrosis, caused by premature termination codons (PTCs)
DCC3832 Nv2909 Novel translational readthrough-inducing drug (TRID), rescuing the functional full-length protein expression in genetic diseases, such as cystic fibrosis, caused by premature termination codons (PTCs)
DCC3833 Nv2913 Novel translational readthrough-inducing drug (TRID), rescuing the functional full-length protein expression in genetic diseases, such as cystic fibrosis, caused by premature termination codons (PTCs)

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