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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC4226 Ppk1-in-8 Novel PPK1 inhibitor, preventing UTI effectively through the disruption of the PPK1 function
DCC4227 pppone Potent and selective antagonist of melanocortin-4 receptor (MC4R)
DCC4228 Ppq-581 Novel anti-influenza agent, interrupting the crucial RNP trafficking, resulting in influenza replication inhibition, preventing virus-induced cytopathic effects
DCC4229 Ppt (water-heme Modulator) Novel Modulator of Water-Heme Interactions in Low-Spin P450 Complexes of CYP2C9d and CYP125A1
DCC4230 Ppxy Budding Inhibitor 4 Novel inhibitor of budding of mVP40 and eVP40 VLPs, blocking mVP40-795 Nedd4 protein-protein interaction.
DCC4231 Ppxy Budding Inhibitor 5 Specific blocker of the MARV VP40 PPxY-host Nedd4 interaction and subsequent PPxY-dependent egress of MARV VP40 VLPs.
DCC4232 Pqa-11 Novel potent neuroprotectant, inhibiting glutamate-induced cell death, caspase-3 activation, and amyloid β1-42-induced cell death, also suppressing mitogen-activated protein kinase kinase 4 (MKK4) and c-jun N-terminal kinase (JNK) signaling activated by n
DCC4233 Pqc-078 Novel inhibitor of IMPDH enzyme
DCC4234 Pqq-tme Novel human double minute 2 (HDM2) inhibitor
DCC4235 Pqsr Antagonist M64 Quorum sensing modulator as a PqsR antagonist
DCC4236 Pradigastat Featured Pradigastat (LCQ-908) is a potent, selective and orally active diacylglycerol acyltransferase 1 (DGAT1) inhibitor. Pradigastat has anti-obesity and anti-diabetic effects.
DCC4237 Pravadoline Maleate Inhibitor of prostaglandin (PG) synthesis
DCC4238 Prazosin Inverse agonist at alpha-1 adrenergic receptors
DCC4239 Prexasertib Monolactate Monohydrate Novel inhibitor of checkpoint kinase 1 (CHK1)
DCC4240 Pridopidine Hydrochloride Inducer of Functional Neurorestoration Via the Sigma-1 Receptor
DCC4241 prmt3 Inhibitor 1 Allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3)
DCC4242 prmt3 Inhibitor 14u Potent and selective inhibitor of protein arginine methyltransferase 3 (PRMT3)
DCC4243 Prmt4-in-1 Novel potent and selective inhibitor of PRMT4 (also known as CARM1)
DCC4244 Prmt5-in-4b14 Novel potent PRMT5 inhibitor, exhibiting potent anti-proliferative activity against a panel of leukemia and lymphoma cells
DCC4245 Prmt5-in-c17 Featured Novel potent, selective, and cell active protein arginine methyltransferase 5 (PRMT5) inhibitor
DCC4246 Prmts Inhibitor A36 Potent inhibitor of protein arginine methyltransferases (PRMTs)
DCC4247 Prmts Inhibitor A9 Potent inhibitor of protein arginine methyltransferases (PRMTs)
DCC4248 Prn1008 Novel, Reversible Covalent BTK Inhibitor for Rheumatoid Arthritis
DCC4249 Prn1126 Novel reversible covalent selective LMP7 inhibitor
DCC4250 pr-nhp5g Antagonist at the NR1/NR2A subtype but an agonist at the NR1/NR2D subtype
DCC4251 Probimane Potent inhibitor of tumor metastasis, inhibiting calmodulin, sialic acid, lipoperoxidation, fibrinogen, cell-movement and the cell-cycle arrest
DCC4252 Procaspase-8 Inhibitor 63-r Novel selective procaspase-8 (Pro-C8) Inhibitor covalently binding the zymogen, or inactive precursor (pro-form), of caspase-8, but not other caspases
DCC4253 Pro-nbdhex Prodrug of NBDHEX, selectively inhibiting glutathione transferase (GST P1-1) with better water solubility, and more potent anticancer activities
DCC4254 Protac 14a Novel potent cereblon degrader with DC50 of 200 nM, and 64% protein degradation, as quantified by western blot
DCC4256 Protac Cp17 Novel highly potent degrader against EGFRL858R/T790M and EGFRdel19, reaching the lowest DC 50 values among all reported EGFR-targeting PROTACs

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