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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC4466 Ro5234444 Orally active chemokine receptor CCR2 antagonist preventing glomerulosclerosis and renal failure in type 2 diabetes
DCC4467 Ro5527239 Novel potent, orally available GPBAR1 agonist
DCC4468 Ro-57-bpyne Novel γ-secretase modulator photoaffinity probe, identifying distinct allosteric binding sites on presenilin that can be exploited to reduce levels of pathogenic Aβ species
DCC4469 Ro6800020 Potent γ-secretase modulator (GSM)
DCC4470 Ro6842262 Novel potent and selectve LPA1 antagonist, attenuating NHLF human lung fibroblast cell proliferation and contraction in vitro, reducing plasma histamine levels in mouse LPA-challenge model
DCC4471 Ro7101556 Novel potent γ-secretase modulator (GSM) with high solubility, balanced lipophilicity, and showing no phototoxicity and PIK4CB side bing activity
DCC4472 Robalzotan Selective antagonist at the 5-HT1A receptor
DCC4473 Rocepafant Platelet-activating factor (PAF-R) antagonist, selectively for intracellular PAF binding sites
DCC4474 Rockii-in-di Novel potent competitive inhibitor of Rho-associated coiled-coil-containing protein kinase 2 (ROCKII)
DCC4475 Rock-in-(r)14f Novel potent ROCK inhibitor
DCC4476 Rock-in-32 Potent Rho--​kinase (ROCK) inhibitor
DCC4477 Rock-in-d1 Novel potent and selective ROCK inhibitor
DCC4478 Rock-in-d2 Novel potent and selective ROCK inhibitor
DCC4479 Rock-in-d3 Novel potent and selective ROCK inhibitor
DCC4480 Rohitukine Anti-cancer agent, acting through gastrin antagonism and H /K -ATPase inhibition, modulating apoptosis pathways, antidyslipidemic, antiadipogenic, gastroprotective, antifertility, and antileishmanial
DCC4481 Ronifibrate Lipid modifying agent; Antihyperlipidemic and antiarteriosclerotic
DCC4482 Rooperol Novel p38α kinase inhibitor; Antioxidant
DCC4483 Ropizine Allosteric modulator of dextromethorphan binding to high-affinity sigma receptors
DCC4484 Ror Modulator I The first potent inverse agonist of retinoid-related orphan receptor (ROR) with dual selectivity for RORβ and RORγt
DCC4485 Rorgammat Agonist 8-074 Novel potent and selective RORγt agonist, showing robust antitumor efficacy in syngeneic tumor models and improving the efficacy of anti‑PD‑1 in a murine lung cancer model
DCC4486 Rorgammat Inhibitor I Novel RORgammaT inhibitor
DCC4487 Rorγt Agonist Novel RORγt agonist
DCC4488 Rorγt-inverse-agonist-1j Novel potent RORγt inverse agonist
DCC4489 Rosma-18-d6 Novel potent and selective CB2 probe (Ki for CB2: 0.8 nM and >12000 selectivity over CB1)
DCC4490 Ros-modulator-3b Novel P2X3 antagonist
DCC4491 Rostaporfin Photosensitiser for the treatment of age-related macular degeneration
DCC4492 Rovafovir Novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor
DCC4493 Rovafovir Etalafenamide Prodrug of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148
DCC4494 Roxatidine Acetate Specific and competitive H2 receptor antagonist
DCC4495 Rp-001 Hydrochloride Potent agonist of S1P1 receptors

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