| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC73909 | ARUK2001607 Featured | ARUK2001607 is a potent, selective and brain penetrant PI5P4Kγ inhibitor with binding KD of 7.1 nM, pIC50 of 7.1 (PI5P4Kγ+). |
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| DC73910 | ARUK200282 | ARUK200282 is a potent, isoform-selective PI5P4Kα inhibitor with pIC50 of 8.0, selective over PI5P4Kβ and PI5P4Kγ. |
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| DC73911 | ARUK2002821 | ARUK2002821 is a potent, selective PI5P4Kα inhibitor with pIC50 of 8.0, >1000-fold selective over PI5P4Kγ. |
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| DC73912 | ARUK2007145 | ARUK2007145 is a potent, selective and cell-active PI5P4Kα/γ dual inhibitor with pIC50 of 7.3/8.1, resepctively, shows no activity against PI5P4Kβ. |
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| DC73913 | ASB17061 | ASB17061 (ASB-17061) is an orally active, selective chymase inhibitor with IC50 of 0.03 uM and 0.02 uM for mMCP-4 and human chymase, respecitvely. |
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| DC73914 | ASN 90 | ASN90 is a potent, selective, substrate-competitive O-GlcNAcase (OGA) inhibitor with IC50 of 10.2 nM. |
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| DC73915 | ASP7967 | ASP7967 (ASP-7967) is a cell-permeable and low-toxic compound of RNA aptamer AC17-4 with SPR binding Kd of 12 nM, activates gene expression (>10-fold) in aptazyme-based riboswitches with EC50 of 2.3 uM. |
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| DC73916 | AZ13792138 | AZ13792138 is a highly potent, selective inhibitor of MTH1 (NUDT1) with Kd/IC50 of 0.4/0.5 nM. |
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| DC73917 | BCL3ANT | BCL3ANT (NSC-659509) is a small molecule inhibitor of Bcl-3-mediated cyclin D1 expression, reduces cyclin D1 luciferase activity in Bcl-3-overexpressing melanoma cells with IC50 of 40.4 uM. |
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| DC73918 | BD442618 | BD442618 (BD 442618) is a potent small-molecule GPR52 agonist. |
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| DC73919 | BD50265 | BD50265 (BD 50265) is a potent small-molecule GPR52 agonist. |
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| DC73920 | BI-0955 | BI-0955 is an inactive HSD17B13 control compound for BI-3231. |
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| DC73921 | BI-9466 | BI-9466 (BI 9466) is the negative control of NSD3-PWWP1 domain chemical probe BI-9321. |
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| DC73922 | BiTud | BiTud is a bivalent inhibitor against TDRD3 with binding Kd of 6 uM for tandem Tudor chimera, blocks the recruitment of TDRD3 by the two methylated arginines of G3BP1, suppress the phase separation of methylated G3BP1, TDRD3, and RNAs, and in turn inhibit |
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| DC73923 | BK697 | BK697 is a small molecule targeting FIRΔexon2, potentially interacts with FIRΔexon2, significantly suppresses the FIRΔexon2 expression and inhibits tumor cell growth and several rRNA expressions. |
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| DC73924 | BNZ-1 | BNZ-1 (BNZ132-1-40) is a pegylated peptide, BNZ132-1 conjugated with methoxy-PEG40 maleimide molecule via a specific linker (CGSGG), specifically binds the γc receptor to selectively block IL-2, IL-15 and IL-9 signaling. |
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| DC73925 | BNZ132-1 | BNZ132-1 (QITISILSQINRVFHEKFI) is a specific peptide inhibitor for the IL-2/IL-15 subfamily, directly binds to the γc molecule (CD132). |
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| DC73926 | BR102910 | BR102910 (BR 102910) is a novel potent, selective, oral fibroblast activation protein (FAP) inhibitor with IC50 of 1 nM. |
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| DC73927 | BRD4780 | BRD4780 is a small molecule that releases MUC1-fs from TMED9-enriched compartments and promotes its anterograde trafficking to the lysosome, directly binds to TMED9. |
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| DC73928 | BRD8518 | BRD8518 is a specific small molecule TRIB1 inducer, modulates expression of the key genes involved in VLDL production and in LDL clearance in HepG2 cells. |
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| DC73929 | BRM011 | BRM011 (dual BRM and BRG1 inhibitor 11) is a potent, selective, allosteric dual BRM and BRG1 inhibitor with IC50 of <5 nM for both. |
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| DC73930 | Butaselen | Butaselen is a small molecule inhibitor of thioredoxin reductase (TrxR)/thioredoxin (Trx) with anti-tumor activity, inhibits the growth of various human cancer cell lines. |
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| DC73931 | C105SR | C105SR is small-molecule cyclophilin inhibitor with IC50 of 5 nM for inhibition of CypD PPIase activity and 9 nM for mitochondrial swelling. |
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| DC73932 | C10M | C10M is a small molecule inhibitor of C-reactive protein (CRP), inhibits the binding of pCRP to the physiological ligand phosphocholine (PC) with IC50 of 1.5 mM in ELISA assays. |
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| DC73933 | C902 Featured | C902 is a small-molecule inhibitor targeting LIN28-let-7 interaction, shows dose-dependent inhibition in an EMSA validation assay with IC50 of 5 uM. |
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| DC73934 | Calmirasone1 | Calmirasone1 (Calmirasone 1) is a novel and potent covalent calmodulin (CaM) inhibitor with Kd of 0.87 uM. |
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| DC73935 | CARD8 activator CQ31 | CARD8 activator CQ31 is a small molecule that selectively activates CARD8. |
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| DC73936 | CASK chemical probe 18 | CASK chemical probe 18 is a highly potent and selective CASK inhibitor with IC50 of 22 nM. |
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| DC73937 | CB253 | CB253 is a small molecule that selectively binds the hairpin form of r(G4C2)exp, inhibiting mechanisms that drive c9ALS/FTD pathobiology. |
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| DC73938 | CBK034026C | CBK034026C is a small molecule targeting metabolic vulnerabilities caused by N-acetyltransferase 2 (NAT2) activity, exhibits specific toxicity towards colorectal cancer (CRC) cells with high NAT2 activity. |
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