| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC73969 | DFO-5 | DFO-5 (Oseltamivir Epoxy Impurity) is an oseltamivir impurity. |
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| DC73970 | DFTD | DFTD is a time-dependent, reversible and covalent inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K) targeting of Cys-146, DFTD binds to the ATP binding site of eEF-2K. |
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| DC73971 | DHAB | DHAB is a potent, specific small molecule inhibitor of kidney ADPR-cyclase with IC50 of 2.5 nM, does not inhibit CD38, spleen, heart or brain ADPR-cyclase activity in vitro. |
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| DC73972 | DHC-156 | DHC-156 is a covalent small molecule inhibitor of oncogenic transcription factor brachyury, selectively binds to brachyury, DHC-156 is potent brachyury downmodulator with DC50 of 4.1 uM. |
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| DC73973 | Dibutepinephrine | Dibutepinephrine is a sympathomimetic compound. |
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| DC73974 | Dichloroallyl lawsone | Dichloroallyl lawsone (Dichlorolapachol, DCL, NSC-126771) is a synthetic analogue of the antimalarial lapachol, inhibits mitochondrial dihydroorotate dehydrogenase (DHODH) with antineoplastic activity. |
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| DC73975 | Dihydrorhodamine 123 | Dihydrorhodamine 123 (DHR 123) is a cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) such as peroxide and peroxynitrite.. |
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| DC73976 | DiI | Dil (DiIC18(3)) is a fluorescent neuronal tracer that labels cell bodies, axons, dendrites, and dendritic spines. |
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| DC73977 | DKC1125 | DKC1125 is a small molecule KSRP-binding compound that specifically inhibits the oncogenic KITENIN complex, suppresses distant metastasis of colorectal cancer (CRC). |
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| DC73978 | DS07551382 | DS07551382 (DS 07551382) is potent, selective and orally active PTDSS1 (phosphatidylserine synthetase 1), suppresses phosphatidylserine (PS) production activity of PTDSS1 (IC50=100 nM) in cell-free assays, but not that of PTDSS2. |
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| DC73979 | DS21150768 | DS21150768 is a potent selective and orally active hematopoietic progenitor kinase 1 (HPK1) inhibitor with IC50 of 3.27 nM in cell-free HPK1 assays, binds to HPK1 with an affinity constant (KD) of 6.08 nM. |
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| DC73980 | DS55980254 Featured | DS55980254 (DS 55980254) is potent, selective and orally active PTDSS1 (phosphatidylserine synthetase 1) inhibitor, suppresses phosphatidylserine (PS) production activity of PTDSS1 (IC50=100 nM) in cell-free assays, but not that of PTDSS2. |
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| DC73981 | DS68591889 | DS68591889 (PTDSS1i) is a potent, selective phosphatidylserine synthase 1 (PTDSS1) inhibitor, highly sellective over PTDSS2, induces phospholipid imbalance in a wide range of cancer cells. |
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| DC73982 | DSHN-OMe | DSHN-OMe (DSHN methyl ester) is a small molecule modulator of NR0B2, effectively reduces induction of LXR target gene ABCA1 by GW3965 (1 uM) in BMDMs with IC50 of 3.8 uM, reduces regulatory T cell expansion and impede breast cancer progression. |
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| DC73983 | DSK638 | DSK638 (DSK-638) is a potent small moelcule RECK inducer, binds histone deacetylases (HDACs) with IC50 of 5-10 uM for HDAC1/3. |
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| DC73984 | DSRM-3716 | DSRM-3716 (DSRM3716, 5-iodoisoquinoline) is a potent and selective inhibitor of NADase SARM1 with IC50 of 75 nM, displays selectivity against various NAD metabolizing and pathway enzymes (e.g., NAMPT and NMNAT). |
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| DC73985 | Ederimotide | Ederimotide (WT1-A1) is a synthetic peptide derived from nonamer sequences of the Wilms tumor protein 1 (WT1), increases human T-cell responses and shows potential as cancer vaccine. |
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| DC73986 | EML417 | EML417 is a small molecule that selectively interactes with the Tudor domain of PHF20. |
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| DC73987 | Endosidin17 | Endosidin17 (ES17) is a small molecule targets retromer component VPS35, binds to VPS35 Impairs interaction with RABG3f, causes dose-dependent stabilization of VPS35 with EC50 of 0.9 uM. |
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| DC73988 | EP055 | EP055 (EP-055) is a small molecule that targets EPPIN on the surface of sperm and inhibits motility (IC50=199.5 uM, CASA assay using human sperm), binds to the C-terminal domain of EPPIN. |
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| DC73989 | EPIC-0412 | EPIC-0412 is a small-molecule inhibitor that enhances the chemotherapeutic effect of temozolomide (TMZ) by acting on the p21-E2F1 DNA damage repair axis and ATF3-p-p65-MGMT axis. |
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| DC73990 | Equilin | Equilin (7-Dehydroestrone) is a highly potent 3βHSD1 inhibitor with IC50 of 2.8 nM in VCaP cells, also inhibits the activity of purified 3βHSD1 with SPR KD of 2.23 uM. |
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| DC73991 | Ethanimidothioic acid | Ethanimidothioic acid (R5421) is an inhibitor of platelet scramblase activity. |
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| DC73992 | EVT-701 | EVT-701 is a highly potent, selective, and safe mitochondrial complex 1 (MC1) inhibitor, reduces NADH abundance with IC50 of 300 nM. |
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| DC73993 | F12511 | Eflucimibe (F 12511) is a highly potent, selective inhibitor of acyl-CoA: cholesterol acyltransferase ( ACAT/SOAT) with IC50 of 3, 7, and 71 nM in whole cell assays using HepG2, CaCo-2 and THP-1 cell lines, respectively. |
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| DC73994 | F759 | F759 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets. |
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| DC73995 | F83236 | F83236 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets. |
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| DC73996 | FDW028 | FDW028 is a potent and highly selective small-molecule inhibitor of fucosyltransferase 8 (FUT8) with binding KD value of 5.486 uM, displays no affinity against other FUTs, shows potent anti-CRC activities. |
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| DC73997 | Feeblin | Feeblin (SLC15A4 inhibitor C5) is a small molecule inhibitor of the proinflammatory TLR7/8/9-IRF5 pathway (IC50=1.6 uM) by disrupting the SLC15A4-TASL adapter module, Feeblin is an IRF5 pathway-specific inhibitor. |
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| DC73998 | FK3453 | FK3453 (FK 3453) is a novel inhibitor of thymic stromal lymphopoietin (TSLP) production, reduces both TSLP protein levels and mRNA levels both in vitro and in vivo. |
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