| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC74600 | Lotiglipron Featured | Lotiglipron (PF-07081532) is an orally active GLP-1R agonist. It reduces glucose and body weight, and has the potential to be used in Type 2 diabetes mellitus (T2DM) research. |
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| DC74601 | Solutol HS-15 | Solutol HS-15(Polyethylene glycol 12-hydroxystearate) is a Macrogol 15 hydroxy stearate, which improves permeability by disrupting the membrane structure/fluidity change. |
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| DC74602 | Potassium clavulanate cellulose | Potassium clavulanate cellulose (Potassium clavulanate:cellulose (1:1)) is a mixture of potassium clavulanate and cellulose, is a bacterial β-lactamase inhibitor. Potassium clavulanate with the combination of amoxicillin can be used for the research of different infections caused by bacteria, such as sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin. |
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| DC74603 | 2,4-Thiazolidinedione | 2,4-Thiazolidinedione (Thiazolidinedione), an insulin sensitizer, is a specific agonist of peroxisome proliferator-activated receptor (PPAR)γ. Thiazolidinedione treatment corrects impaired muscle insulin action in vivo. |
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| DC74604 | Biotin-(L-Thyroxine) | Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine. L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4). |
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| DC74605 | EDI048 | EDI048 (compound 1.16) is an orally active Cryptosporidium PI4K inhibitor for the research of cryptosporidiosis. |
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| DC74606 | Enavermotide | Enavermotide (UCP2) is an immunological agent for active immunization (antineoplastic). |
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| DC74607 | Sucantomotide | Sucantomotide is an immunological agent for active immunization (antineoplastic). |
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| DC74608 | Zelenectide | Zelenectide (BCY8116) is a Bicycle peptide targeting to Nectin-4, which is a cell adhesion molecule. Zelenectide serves as a Bicycle tumor-targeted immune cell agonist. |
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| DC74609 | 9-Deazaguanine | 9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP). |
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| DC74610 | XY-52 | XY-52 (Compound 32) is a Stimulation-2 (ST2) inhibitor, with an IC50 value of 5.68 μM in AlphaLISA assay, and 4.59 μM in HEK-Blue assay. XY-52 increases proinflammatory T-cell proliferation. XY-52 reduces the plasma sST2 and IFNγ biomarkers in the graft versus host disease (GVHD) mice model. |
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| DC74611 | Civorebrutinib | Civorebrutinib (WS-413) is a Bruton's tyrosine kinase inhibitor with antineoplastic effect. |
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| DC74613 | Tegomil fumarate | Tegomil fumarate is an immunomodulator. |
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| DC74614 | Ucasareotide dasaroxetan | Ucasareotide dasaroxetan (SarTATE) is diagnostic agent with antineoplastic effect. |
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| DC74615 | BC-05 | BC-05 is an orally active and potent inhibitor of CD13 and proteasome. BC-05 has an IC50 value of 0.13 μM for human CD13 and an IC50 value of 1.39 μM for the 20S proteasome. BC-05 can be used in multiple myeloma research. |
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| DC74616 | BTM-3566 | BTM-3566 is an OMA1 activator. BTM-3566 activates the mitochondrial stress response. BTM-3566 induces apoptosis in diffuse large B-cell lymphomas (DLBCL) cell lines. |
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| DC74617 | Arecaidine hydrobromide | Arecaidine hydrobromide, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrobromide is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake. |
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| DC74618 | Guvacine hydrobromide | Guvacine hydrobromide, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine hydrobromide inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively. |
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| DC74619 | Ancistrotecine B | Ancistrotecine B (Compound 2) is a Nav1.7 channel inhibitor (IC50: 0.73 μM). Ancistrotecine B relieves inflammatory pain in mice. |
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| DC74620 | OATD-02 | OATD-02 is an orally active, competitive, reversible, noncovalent dual inhibitor of Arginase1 and 2. OATD-02 is a slow offset inhibitor, blocking intracellular arginases with IC50s of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1), respectively. OATD-02 abolishes tumor immunosuppression induced by both arginases. OATD-02 can be used for melanoma study. |
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| DC74621 | Icalcaprant | Icalcaprant is a kappa-opioid receptor antagonist. |
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| DC74622 | Igermetostat | Igermetostat is EZH2 inhibitor, used in cancer research in vivo and in vitro. |
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| DC74623 | SPC-180002 | SPC-180002 is a SIRT1/3 dual inhibitor, with IC50 values of 1.13 and 5.41 μM, respectively. SPC-180002 disturbs redox homeostasis via ROS generation, which leads to an increase in both p21 protein stability and mitochondrial dysfunction. SPC-180002 strongly inhibits cell cycle progression and cancer cell growth. SPC-180002 activates the Nrf2 signaling pathway. |
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| DC74624 | Tibremciclib | Tibremciclib is a CDK4 inhibitor with antineoplastic activity. |
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| DC74625 | Votoplam | Votoplam is a gene splicing modulator, used to inhibit Huntington's disease. |
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| DC74626 | Lacutoclax | Lacutoclax is a Bcl-2 inhibitor with antineoplastic activity. |
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| DC74627 | NSC89641 | NSC89641 inhibits MERS-CoV Mpro, with an IC50 value < 3.5 μM. NSC89641 exhibits the high inhibitory potency against SARS-CoV-2 Mpro enzymatic activity, with an IC50 of 3.05 μM. |
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| DC74628 | PC-766B | PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na+, K+-ATPase. |
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| DC74629 | Zevotrelvir | Zevotrelvir (Compound 52) is a coronavirus inhibitor with IC50 ranges of <0.1 μM and <0.1mM for 229E hCoV and SARS-CoV-23C-like (3CL) proteases, respectively. Zevotrelvir has the potential to study viral infections. |
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| DC67028 | Pegaptanib Featured |
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