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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC20921 CDK5 inhibitor 20-223 CDK5 inhibitor 20-223 (CP 668863) potent, selective, ATP-competitive CDK2/5 inhibitor with IC50 of 6.0 and 8.8 nM for CDK2/CyclinE and CDK5/p35, with little to no activity against CDK1/4/6/7/9.
DC12528 CDK9 inhibitor HH1 Featured CDK9 inhibitor HH1 is a novel potent, highly selective CDK9 inhibitor..
DC20335 CDK9-IN-8 Featured CDK9-IN-8 is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition.
DC9478 CDK9-IN-1 CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection.
DC23138 CDK-I73 Featured CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM, shows cytotoxicity against a broad CLL samples with mean LD50 of 80 nM.
DC9390 CDK-IN-2 Featured CDK-IN-2 is a potent and sepecific CDK inhibitor.
DC11393 CDM-NAG Featured CDM-NAG is a useful tool compound to deliver the siRNA.
DC10948 CDN1163 Featured CDN1163 (CDN-1163) is a small molecule, allosteric activator of SERCA2, dose-dependently increases the Vmax of SERCA2 Ca2+-ATPase activity in ER microsomes; increases Ca2+-ATPase activity and significantly enhances Ca2+ uptake into the ER, attenuates H2O2-stimulated cell death in HEK cells; improves glucose homeostasis and metabolic parameters, increases glucose tolerance in ob/ob mice; CDN1163 reduces lipid accumulation and decreases lipogenesis in obese mice livers.
DC20879 CDP-840 CDP-840 (CDP840.
DC20880 CDP-840 hydrochloride CDP-840 (CDP840.
DC23463 CDPPB Featured CDPPB is a potent, selective, brain penetrant positive allosteric modulator of mGlu5 receptor with EC50 of 10 nM and 20 nM for human and rat mGluR5, respectively.
DC22446 CE-224535 CE-224535 (PF-04905428) is a potent and selective P2X7 receptor antagonist with IC50 of 1.4 nM (inhibition of the release of lL-1b from monocytes stimulated by ATP).
DC20881 CE-245677 CE-245677 is a potent, selective, orally active, dual Tie2/Trk kinase inhibitor with IC50 of 4.7 nM, 1 nM for Tie2 and TrkA/B, respectively.
DC20336 CE3F4 Featured CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity.
DC23912 Cecropin B Cecropin B is an antimicrobial peptide with MICs(0.5 to 16 ug/ml) against Gramnegative strains.
DC20987 Cedazuridine Featured Cedazuridine (E7727) is a novel cytidine deaminase inhibitor, and a componet of ASTX727 for treatment of hematologic malignancies..
DC3170 Cediranib Featured Cediranib (AZD2171) is a highly potent VEGFR2 inhibitor with IC50 of 0.5 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM.
DCAPI1386 Cefdinir (Omnicef) Cefdinir (Omnicef)
DCAPI1024 Cefditoren pivoxil Cefditoren pivoxil
DC8686 Cefetamet pivoxil hydrochloride Cefetamet pivoxil hydrochloride is an oral third generation cephalosporin antibiotic.
DC9358 Cefmenoxime (hydrochloride) Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic.
DCAPI1038 Cefoselis sulfate Cefoselis sulfate
DC20190 Cefoxitin Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
DC8067 Cefozopran Featured Cefozopran (SCE-2787) is a new parenteral cephalosporin, against experimental infections in mice.
DC9356 Cefpiramide (sodium) Cefpiramide sodium (SM-1652; Wy-44635) is a new Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.
DC8687 Cefpirome sulfate Cefpirome Sulfate is a fourth generation cephalosporin antibiotic.
DCAPI1033 Cefprozil hydrate (Cefzil) Cefprozil hydrate (Cefzil)
DC9355 Ceftibuten (dihydrate) Ceftibuten dihydrate is a third-generation cephalosporin antibiotic.
DC12245 Ceftizoxime Ceftizoxime is a bacterial inhibitor which acts by interfering with bacterial cell wall synthesis and inhibiting cross-linking of the peptidoglycan.
DCAPI1155 Celastrol Featured Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM.

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