Cat. No. | Product name | CAS No. |
DC23181 |
(R)-GNE-140
Featured
(R)-GNE-140 (GNE-140) is a novel potent, selective lactate dehydrogenase (LDH) inhibitor with IC50 of 3, 5, and 5 nM for LDHA, LDHB, and LDHC, respectively. |
2003234-63-5 |
DC20290 |
(R)-HZ05
(R)-HZ05 is a potent DHODH inhibitor with IC50 of 11 nM, accumulates cancer cells in S-phase, increases p53 synthesis, and synergizes with an inhibitor of p53 degradation (Nutlin-3a) to reduce tumor growth in vivo.. |
2097360-28-4 |
DC10521 |
(R)-IMPP
Featured
(R)-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9; IC50 = 4.8 µM). |
2133832-83-2 |
DC9092 |
(R)-Lansoprazole
(R)-Lansoprazole is a proton pump inhibitor which prevents the stomach from producing acid. |
138530-94-6 |
DC12403 |
(R)-ND-336
Featured
(R)-ND-336 is a potent and selective small-molecule MMP-9 inhibitor with Ki of 19 nM, weakly inhibits MMP-2 and MMP-14 (Ki=127 and 119 nM), poorly inhibits other MMPs (Ki>10 uM). |
2252493-33-5 |
DC11488 |
USP7-IN-4
(R)-USP-IN-4 is a highly potent, selective, allosteric USP7 inhibitor with IC50 of 6 nM in FP assays. |
2196243-57-7 |
DC20594 |
(R)-ZINC-3573
Featured
(R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases. |
2089389-15-9 |
DC20247 |
(R,R)-BNC375
Featured
(R,R)-BNC375 is a potent, selective, and orally available type I positive allosteric modulator of α7 nAChRs. |
|
DCAPI1481 |
Sulpiride
(RS)-(±)-Sulpiride is a selective postsynaptic D2DR inhibitor. |
15676-16-1 |
DC23000 |
(-)-Perillyl alcohol
Featured
(S)-(-)-Perillyl alcohol is a monoterpenoid compound found in the essential oils of cherries, lavender and spearmint. |
536-59-4 |
DC9581 |
(S)-(+)-Rolipram
(S)-(+)-Rolipram is a PDE4-inhibitor and an anti-inflammatory agent, less potent than its R enantiomer. |
85416-73-5 |
DC26029 |
(S)-4CPG
(S)-4CPG, also known as (S)-4-Carboxyphenylglycine, is a novel orally active metabotropic glutamate receptor 1 antagonist. |
134052-73-6 |
DC23811 |
(S)-BAY-293(BAY293 S-enantiomer)
(S)-BAY-293 (BAY293 S-enantiomer) is the S-enantiomer of BAY-293 as a negative control compound.. |
2244904-69-4 |
DC8451 |
(S)-Equol
Featured
(S)-Equol preferentially binds ERβ (Ki = 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERα (Ki = 6.41 nM). |
531-95-3 |
DC20595 |
(S)-FQI1
(S)-FQI1 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.93 uM, approximately 2-fold more active than the racemate FQI-1. |
1373209-39-2 |
DC9368 |
(S)-Gossypol (acetic acid)
(S)-Gossypol acetic acid is a inhibitor of Bcl-2, potently induce cell death in Jurkat cells overexpressing Bcl-2 (IC50, 18.1μM) or Bcl-xL (IC50, 22.9μM). |
1189561-66-7 |
DC20017 |
(S)-Mapracorat
(S)-Mapracorat is a selective and less active glucocorticoid receptor agonist. |
887375-15-7 |
DC12085 |
(S)-Metolachor
(S)-Metolachor, a derivative of aniline, is a major pesticide in use. |
87392-12-9 |
DC9137 |
Timolol Maleate
Featured
(S)-Timolol maleate, is a potent non-selective β-adrenergic receptor antagonist (Ki values are 1.97 and 2.0 nM for β1 and β2 receptor subtypes respectively). |
26921-17-5 |
DC24129 |
(S)-Willardiine
(S)-Willardiine is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 uM.. |
21416-43-3 |
DC26120 |
(Z)-4-hydroxy Tamoxifen
Featured
(Z)-4-hydroxy Tamoxifen is a major phase I metabolite of tamoxifen, a well-known estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium. |
68047-06-3 |
DC10396 |
(Z)-Mutagenic Impurity of Tenofovir Disoproxil
(Z)-Mutagenic Impurity of Tenofovir Disoproxil is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucia |
1464851-21-5 |