Cat. No. | Product name | CAS No. |
DC73624 |
FP802
FP802 is a potent neuroprotectant and small molecule inhibitor of TwinF interface, shows selective elimination of eNMDAR-mediated toxicity via disruption of the NMDAR/TRPM4 death signaling complex, while sparing the vital physiological functions of synapt |
61694-81-3 |
DC73625 |
GluN2A PAM (R)-9
GluN2A PAM (R)-9 is a potent, brain penetrant, GluN2A-selective positive allosteric modulator with EC50 of 0.51 uM, Emax 350%. |
|
DC73626 |
Org 26576
Org 26576 (MK 8777. |
1026791-61-6 |
DC73627 |
PTC-174
PTC-174 is a selective, positive allosteric modulator of NMDA receptors containing GluN2C or GluN2D subunits with EC50 of 4.1 uM (GluN1/2C) and 5.7 uM (GluN1/2D). |
2230984-40-2 |
DC73628 |
UBP1700
UBP1700 is a subtype-selective competitive antagonist of GluN2C/2D-containing NMDA receptors with Ki of 7-9 nM, 50-fold selectivity over GluN2A and GluN2B. |
2550326-84-4 |
DC73629 |
UBP791
UBP791 is a subtype-selective competitive antagonist of GluN2C/2D-containing NMDA receptors with Ki of 80-90 nM, 50-fold selectivity over GluN2A and GluN2B. |
2550326-75-3 |
DC73630 |
UBP792
UBP792 is a novel negative allosteric modulator (antagonist) of NMDA receptors, displays partial subtype-selectivity by having a varied maximal inhibition of GluN2A-, GluN2B-, GluN2C-, and GluN2D-containing receptors (52%, 70%, 87%, 89%, respectively) wit |
2316816-83-6 |
DC73631 |
ZCAN155
ZCAN155 is a small molecule that prevents AMPA-mediated excitotoxicity (IC50=35 nM) by targeting an allosteric binding site of AMPA glutamate receptor 2 (GluA2), restores neurological function and myelination. |
2485743-34-6 |
DC73632 |
ZCAN262
ZCAN262 is a small molecule that prevents AMPA-mediated excitotoxicity (IC50=8.5 nM) by targeting an allosteric binding site of AMPA glutamate receptor 2 (GluA2). |
|
DC73633 |
(S)-CE-123
(S)-CE-123 is a specific small molecule dopamine transporter (DAT) inhibitor, improves memory acquisition and memory retrieval. |
2378384-49-5 |
DC73634 |
CDTP-32476
CDTP-32476 is a potent slow-onset dopamine reuptake blocker with an affinity of 8.6 nM, CDTP-32476 is moderately selective (14-fold) versus NE reuptake blockade with little effect on the SERT. |
2650890-59-6 |
DC73635 |
D-578
D-578 is a potent, orally active triple monoamine reuptake inhibitor with Ki values of 16.2. 16.2, 3.23 nM, and 29.6, 20.6, 6.10 nM for the rat brain and cloned human dopamine, serotonin and norepinephrine transporters, respectively. |
2454461-06-2 |
DC73636 |
FFN200
FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate, and the first probe to selectively trace monoamine exocytosis in both neuronal cell culture and brain tissue. |
2080306-26-7 |
DC73637 |
GZ-11608
GZ-11608 is a potent and selective vesicular monoamine transporter-2 (VMAT2) inhibitor with Ki of 25 nM, GZ-11608 (EC50=620 nM) released vesicular dopamine 25-fold less potently than it inhibited VMAT2 dopamine uptake. |
2141974-01-6 |
DC73638 |
GZ-794A
GZ-794A is a potent, selective inhibitor of vesicular monoamine transporter-2 (VMAT2) with Ki of 30 nM, inhibits methamphetamine-evoked endogenous dopamine release with IC50 of 0.4 uM, shows potential for treatment for methamphetamine abuse. |
1392205-38-7 |
DC73639 |
JJC8-016
JJC8-016 is a potent, Modafinil-derived dopamine transporter (DAT) ligand with Ki of 116 nM, attenuates compulsive-like methamphetamine self-administration in rats. |
140890-64-8 |
DC73640 |
JJC8-088
JJC8-088 is a potent, Modafinil-derived dopamine transporter (DAT) ligand with Ki of 2.53 nM. |
1627576-82-2 |
DC73641 |
JJC8-091
JJC8-091 is a potent, Modafinil-derived dopamine transporter (DAT) ligand with Ki of 16.7 nM, attenuates compulsive-like methamphetamine self-administration in rats. |
1627576-64-0 |
DC73642 |
LQFM215
LQFM215 (LQFM-215) is a synthetic L-proline transporter (PROT/SLC6A7) inhibitor, inhibits proline uptake in hippocampal synaptosome with IC50 of 20.4 uM, present neuroprotective potential. |
|
DC73643 |
Lu AF60097
Lu AF60097 is a high affinity, allosteric inhibitor of serotonin transporter (SERT) inhibitor with IC50 of 31 nM for inhibition of [3H]IMI dissociation, targets the extracellular vestibule (S2 site). |
2507890-46-0 |
DC73644 |
SRI-32743
SRI-32743 is a novel allosteric modulator of dopamine transporter (DAT), attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter. |
1940118-42-2 |
DC73645 |
ZINC000006658090
ZINC000006658090 (Compound 8090) is a highly potent, selective and non-competitive inhibitor of serotonin transporter (SERT) with Ki of 14 nM. |
887625-25-4 |