| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC47553 | Mulberrofuran G | Mulberrofuran G protects ischemic injury-induced cell death via inhibition of NOX4-mediated ROS generation and ER stress. Mulberrofuran G shows moderate inhibiting activity of hepatitis B virus (HBV) DNA replication with the |
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| DC47563 | MAO-B-IN-2 | MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC50 values of 0.51 and 7.00 μM, respectively. |
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| DC47564 | (+)-Cinchonaminone | (+)-Cinchonaminone shows monoamine oxidase (MAO) inhibitory activity. |
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| DC47565 | Ladostigil hemitartrate | Ladostigil (TV-3326) hemitartrate is a dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO), with an IC50 of 37.1 and 31.8 μM for MAO-B and AChE, reapectively. Ladostigil hemitartrate could increase cholinergic transmission, prevent the formation of ROS or their actions and be used for the research of depression and Alzheimer's disease. |
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| DC47566 | (S)-Salsolidine | (S)-Salsolidine is a weak monoamine oxidase (MAO) inhibitor (Ki=63 μM). The R enantiomer of Salsolidine is more potent than the S form (Ki=26 μM). |
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| DC47568 | ADAM8-IN-1 | ADAM8-IN-1 is a potent ADAM8 inhibitor with an IC50 value of 73 nM. |
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| DC47596 | IDO-IN-15 | IDO-IN-15 is an IDO1 inhibitor (IC50 < 0.51 nM). |
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| DC47597 | IDO-IN-14 | IDO-IN-14 is an IDO inhibitor with an IC50 value of 0.6928 nM. |
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| DC47631 | Ganoderlactone D | Ganoderlactone D shows inhibitory effects of yeast α-Glucosidase with IC50 values of 41.7 μM. |
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| DC47632 | p-Hydroxyphenethyl trans-ferulate | p-Hydroxyphenethyl trans-ferulate has anti-hyperglycemic（yeast α-glucosidase，IC50 19.24 ± 1.73 µmol L-1）, antioxidant, and anti-inflammatory activities. p-Hydroxyphenethyl trans-ferulate shows inhibiting cancer preve |
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| DC47664 | Indole-3-acetaldehyde | Indole-3-acetaldehyde inhibits Escherichia coli O157:H7 biofilm formation. |
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| DC47665 | 4-Hydroxytryptamine creatinine sulfate | 4-Hydroxytryptamine creatinine sulfate, a tryptamine derivative, is a neurotransmitter agonist. |
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| DC47666 | NMTCA | NMTCA (NMTPRO) is a sulfur-containing N-nitrosamino acid. NMTCA can be used as an indicator of endogenous nitrosation by gas chromatography-thermalenergyanalysis. |
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| DC47693 | Ascochlorin A | Ascochlorin A is a novel and potent hDHODH inhibitor (KD = 3.29 μM) for treatment of triple-negative breast cancer. |
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| DC47694 | DHODH-IN-18 | DHODH-IN-18 is a human DHODH inhibitor (IC50 = 0.2 nM). |
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| DC47695 | Indoluidin E | Indoluidin E selectively inhibits DHODH and suppresses cancer cell growth. |
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| DC47708 | Cathepsin L-IN-2 | Cathepsin L-IN-2 (Z-Phe-Phe-FMK) is a potent and irreversible cathepsin L and cathepsin B inhibitor. |
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| DC47709 | ABP 25 | ABP 25 is an activity-based probe for cathepsin K imaging with excellent potency and selectivity. |
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| DC47712 | GCPII-IN-1 | GCPII-IN-1 is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM. |
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| DC47713 | GCPII-IN-1 TFA Featured | GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM. |
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| DC47714 | (E)-Dehydrodiconiferyl alcohol | (E)-Dehydrodiconiferyl alcohol behaves as good hCA IX and hCA XII dual inhibitors. And (E)-Dehydrodiconiferyl alcohol suppresses the NF-κB nuclear translocation in connective tissue of healing area. |
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| DC47720 | β-Secretase Inhibitor I | β-Secretase Inhibitor I is an extremely potent β-secretase inhibitor with reduced cardiovascular and liver toxicity. |
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| DC47721 | JNJ-67569762 Featured | JNJ-67569762 is a tetrahydropyridine-based BACE1 inhibitor targeting the S3 pocket with IC50 of 2.7 nM and shows 71-fold selectivity over BACE2. |
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| DC47722 | β-Secretase Inhibitor III | β-Secretase Inhibitor III is an extremely selective BACE1 inhibitor (Ki = 0.13 nM). |
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| DC47756 | Plantainoside D | Plantainoside D shows ACE inhibitory activity with IC50 2.17 mM. And plantainoside D is a promising IKK-β inhibitor. |
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| DC47762 | MeDTC | MeDTC (S-Methyl-N,N-diethylthiocarbamate Sulfone), a Disulfiram metabolite, is a potent, irreversible aldehyde dehydrogenase (ALDH) inhibitor. |
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| DC47768 | BMS-963272 Featured | BMS-963272 is a potent, selective MGAT2 inhibitor with IC50 of 7.1 nM/18 nM (hMGAT2/mMGAT2) and shows excellent efficacy, safety, and tolerability profile. |
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| DC47769 | Phenylpyropene C | Phenylpyropene C (S14-95), a JAK/STAT pathway inhibitor, can inhibit IFN-γ mediated expression of the reporter gene (IC50=5.4~10.8 μM). Phenylpyropene C also is an inhibitor of acyl-CoA, with an IC50 of 16.0 μM. |
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| DC47772 | Isonaringin | Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE. |
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| DC47773 | Cyclanoline chloride | Cyclanoline (chloride) shows cholinesterase inhibitory activity. |
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