| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DCZ-290 | Isobavachin | purity >98%,Standard References |
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| DCZ-286 | 8-GERANOPSORALEN | purity >98%,Standard References |
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| DCZ-289 | songorine | purity >98%,Standard References |
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| DC7501 | SKLB1002 Featured | SKLB1002 is a novel and potent VEGFR-2 inhibitor with an IC50 value of 32 nM. |
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| DCC-003 | Vincristine | >98%,Standard References |
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| DC60202 | YUN35454 Featured | YUN35454, also known as LMPTP INHIBITOR 1 is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC50 of 0.8 μM LMPTP-A. LMPTP is a key promoter of insulin resistance and that LMPTP inhibitors would be beneficial for treating type 2 diabetes. YUN35454 was first reported in Nature Chemical Biology (2017), 13(6), 624-632. |
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| DC60203 | JNJ-63576253 HCl Featured | JNJ63576253, also known as TRC253, is a potent and orally active androgen receptor antagonist. TRC253 specifically binds to both wild-type and certain mutant forms of AR, thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot translocate to the nucleus. |
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| DC50005 | CH7233163 | CH7233163 is a novel selective inhibitor of various types of EGFR mutants including L858R/T790M/C797S, L858R/T790M, Del19/T790M, Del19, and L858R, showing potent antitumor activities |
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| DC50006 | Cinobufagin (Cinobufagine) Featured | Cinobufagin, a kind of Chinese materia medica with antitumor effect, is widely used in clinical practice, especially in anti-liver cancer. IC50 value: Target: In vitro: Cinobufagin inhibited proliferation of cancer cells at doses of 0.1, 1, or 10 μM after 2–4 days of culture. Cytotoxicity of cinobufagin on the DU145 and LNCaP cells was dose-dependent. Cinobufagin increased [Ca2+]i and apoptosis in cancer cells after a 24-hr culture as well as caspase 3 activities in DU145 and PC3 cells and caspase 9 activities in LNCaP cells [1]. Cinobufagin suppresses cell proliferation and causees apoptosis in prostate cancer cells via a sequence of apoptotic modulators, including Bax, cytochrome c and caspases [2]. |
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| DC50007 | Etoposide Featured | >98%,Standard References |
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| DC50008 | Colchicine Featured | Colchicine is a potent therapeutic tool against COVID-19. Colchicine is a tricyclic alkaloid that is extracted from the plant Colchicum autumnale. Colchicine acts as a potent inhibitor of tubulin polymerization. |
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| DC83215 | DMAP-BLP | DMAP-BLP is a lipid for RNA and vaccine delivery.DMAP-BLP exhibits optimized bilayer destabilizing and pKa properties leading to highly potent gene silencing in hepatocytes following IV administration that is similar to “gold standard” lipids such as DLinMC3-DMA. |
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